Mm00501578_m1

• Gene Symbol: Runx2
• Gene Name: runt related transcription factor 2
• Gene Aliases: AML3, Cbf, Cbfa-1, Cbfa1, LS3, Osf2, PEBP2aA, Pebp2a1, Pebpa2a
• Chromosome Location: Chr.17: 44495986 - 44814831 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Runx2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001146038.2	NP_001139510.1	2 - 3	292		115
	NM_001271627.1	NP_001258556.1	1 - 2	456		115
	NM_009820.5	NP_033950.2	2 - 3	259		115
GenBank mRNA	AF005936.1	-	1 - 2	410		115
	AF010284.1	-	2 - 3	259		115

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1700002138.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mus musculus, Mouse Stem Cell Pluripotency, Inventoried, Mouse_Stem_Cell, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Runx2

Panther Classification:

Molecular Function -

Runt transcription factor

Gene Ontology Categories:

Process(es)

skeletal system development
osteoblast differentiation
endochondral ossification
osteoblast fate commitment
chondrocyte differentiation
chondrocyte development
osteoblast development
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
positive regulation of gene expression
hemopoiesis
neuron differentiation
T cell differentiation
regulation of ossification
BMP signaling pathway
positive regulation of chondrocyte differentiation
embryonic forelimb morphogenesis
regulation of fibroblast growth factor receptor signaling pathway
odontogenesis of dentin-containing tooth
regulation of odontogenesis of dentin-containing tooth
regulation of osteoblast differentiation
positive regulation of osteoblast differentiation
positive regulation of ossification
negative regulation of smoothened signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell maturation
embryonic cranial skeleton morphogenesis
skeletal system morphogenesis
stem cell differentiation
cellular response to BMP stimulus
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
ATP binding
transcription factor binding
protein domain specific binding
histone deacetylase binding
bHLH transcription factor binding
transcription regulatory region DNA binding
repressing transcription factor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1700020024.mm.1	NM_001146038.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020024.mm.1	NM_001271627.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020024.mm.1	TC1700002138.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1700020012.mm.1	NM_001145920.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020012.mm.1	NM_001146038.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020012.mm.1	NM_001271627.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020012.mm.1	NM_001271630.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020012.mm.1	NM_001271631.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020012.mm.1	NM_009820.5	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020012.mm.1	NR_073425.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020012.mm.1	TC1700002138.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1700020023.mm.1	NM_001271627.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020023.mm.1	TC1700002138.mm.1	MTA TC