Mm00501988_m1

• Gene Symbol: Med1
• Gene Name: mediator complex subunit 1
• Gene Aliases: AI480703, CRSP210, DRIP205, PBP, Pparbp, TRAP220, l11Jus15
• Chromosome Location: Chr.11: 98152154 - 98193314 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Med1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001080118.1	NP_001073587.1	10 - 11	948		67
	NM_013634.2	NP_038662.2	10 - 11	813		67
	NM_134027.2	NP_598788.2	10 - 11	948		67
GenBank mRNA	AF000294.1	-	10 - 11	813		67
	AF332073.1	-	9 - 10	693		67
	AF332074.1	-	9 - 10	693		67
	AK049203.1	-	10 - 11	939		67
	AK054437.1	-	10 - 11	949		67
	AK147199.1	-	10 - 11	925		67
	BC021440.1	-	10 - 11	919		67
	BC079636.1	-	10 - 11	918		67

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100003669.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Med1

Gene Ontology Categories:

Process(es)

negative regulation of transcription by RNA polymerase II
cell morphogenesis
angiogenesis
in utero embryonic development
liver development
embryonic placenta development
lens development in camera-type eye
thyroid hormone mediated signaling pathway
ventricular trabecula myocardium morphogenesis
retinal pigment epithelium development
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription by RNA polymerase I
regulation of transcription by RNA polymerase II
transcription by RNA polymerase II
transcription initiation from RNA polymerase II promoter
thyroid hormone generation
androgen biosynthetic process
multicellular organism development
brain development
heart development
lactation
positive regulation of cell population proliferation
animal organ morphogenesis
positive regulation of gene expression
negative regulation of keratinocyte proliferation
protein ubiquitination
keratinocyte differentiation
monocyte differentiation
intracellular steroid hormone receptor signaling pathway
androgen receptor signaling pathway
animal organ regeneration
positive regulation of intracellular estrogen receptor signaling pathway
mammary gland epithelial cell proliferation
positive regulation of mammary gland epithelial cell proliferation
embryonic heart tube development
embryonic hindlimb morphogenesis
embryonic hemopoiesis
peroxisome proliferator activated receptor signaling pathway
cellular response to hepatocyte growth factor stimulus
megakaryocyte development
mRNA transcription by RNA polymerase II
camera-type eye development
negative regulation of apoptotic process
fat cell differentiation
positive regulation of keratinocyte differentiation
negative regulation of neuron differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription by RNA polymerase II
erythrocyte development
enucleate erythrocyte development
positive regulation of interferon-gamma-mediated signaling pathway
mammary gland branching involved in thelarche
mammary gland branching involved in pregnancy
epithelial cell proliferation involved in mammary gland duct elongation
positive regulation of G0 to G1 transition
ERK1 and ERK2 cascade
regulation of vitamin D receptor signaling pathway
cellular response to epidermal growth factor stimulus
cellular response to steroid hormone stimulus
cellular response to thyroid hormone stimulus
positive regulation of signaling receptor activity
positive regulation of hepatocyte proliferation
regulation of RNA biosynthetic process

Function(s)

RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
core promoter sequence-specific DNA binding
DNA binding
chromatin binding
transcription coregulator activity
transcription coactivator activity
protein binding
transcription factor binding
nuclear receptor binding
estrogen receptor binding
nuclear receptor coactivator activity
chromatin DNA binding
mediator complex binding
signaling receptor activity
vitamin D receptor binding
retinoic acid receptor binding
peroxisome proliferator activated receptor binding
protein-containing complex binding
thyroid hormone receptor binding
LBD domain binding
ubiquitin protein ligase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100033812.mm.1	TC1100003669.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1100033812.mm.1	NM_001080118.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100033812.mm.1	NM_001080118.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100033812.mm.1	NM_013634.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100033812.mm.1	NM_013634.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1100033812.mm.1	NM_134027.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100033812.mm.1	NM_134027.2	Refseq