Mm00503450_m1

• Gene Symbol: Mlh1
• Gene Name: mutL homolog 1 (E. coli)
• Gene Aliases: 1110035C23Rik, AI317206, AI325952, AI561766
• Chromosome Location: Chr.9: 111228228 - 111271786 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Mlh1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_026810.2	NP_081086.2	12 - 13	1498		74
GenBank mRNA	AF250844.1	-	12 - 13	1414		74
	AK004105.1	-	3 - 4	588		74
	AK038265.1	-	12 - 13	1491		74
	AK145646.1	-	12 - 13	1445		74
	AK163861.1	-	11 - 12	2664		74
	AK168849.1	-	12 - 13	1437		74
	BC021815.1	-	12 - 13	1452	4020489	74

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0900003128.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Mlh1

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA poly(A) tail shortening
resolution of meiotic recombination intermediates
somatic recombination of immunoglobulin genes involved in immune response
DNA repair
mismatch repair
double-strand break repair via nonhomologous end joining
cellular response to DNA damage stimulus
cell cycle
male meiosis chromosome segregation
homologous chromosome pairing at meiosis
reciprocal meiotic recombination
male meiotic nuclear division
spermatogenesis
intrinsic apoptotic signaling pathway in response to DNA damage
female meiosis chromosome segregation
somatic hypermutation of immunoglobulin genes
somatic recombination of immunoglobulin gene segments
meiotic metaphase I plate congression
meiotic chromosome segregation
homologous chromosome segregation
isotype switching
negative regulation of mitotic recombination
oogenesis
meiotic spindle midzone assembly
meiotic cell cycle

Function(s)

DNA binding
single-stranded DNA binding
ATP binding
ATP hydrolysis activity
mismatched DNA binding
guanine/thymine mispair binding
MutSalpha complex binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0900026489.mm.1	TC0900003128.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0900026489.mm.1	NM_026810.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900026489.mm.1	NM_026810.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0900026490.mm.1	TC0900003128.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0900026490.mm.1	NM_026810.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900026490.mm.1	NM_026810.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0900026491.mm.1	TC0900003128.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0900026491.mm.1	NM_026810.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900026491.mm.1	NM_026810.2	Refseq