Mm00514993_m1

• Gene Symbol: Gch1
• Gene Name: GTP cyclohydrolase 1
• Gene Aliases: GTP-CH, GTPCH, Gch
• Chromosome Location: Chr.14: 47153895 - 47189402 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Gch1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008102.3	NP_032128.1	3 - 4	614		101
GenBank mRNA	AK150657.1	-	3 - 4	626		101
	AK152571.1	-	3 - 4	626		101
	BC005643.1	-	3 - 4	614	3709238	101
	BC069921.1	-	3 - 4	618	6529016	101
	L09737.1	-	3 - 4	601		101

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1400001930.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Gch1

Panther Classification:

Molecular Function -

hydrolase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

protein complex assembly
tetrahydrobiopterin biosynthetic process
metabolic process
regulation of blood pressure
regulation of lung blood pressure
response to interferon-gamma
response to tumor necrosis factor
vasodilation
dopamine biosynthetic process
pteridine-containing compound biosynthetic process
negative regulation of blood pressure
tetrahydrofolate biosynthetic process
response to pain
neuromuscular process controlling posture
positive regulation of nitric-oxide synthase activity
dihydrobiopterin metabolic process
protein homooligomerization
protein heterooligomerization

Function(s)

nucleotide binding
catalytic activity
GTP cyclohydrolase I activity
calcium ion binding
GTP binding
zinc ion binding
hydrolase activity
GTP-dependent protein binding
protein homodimerization activity
metal ion binding
coenzyme binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1400014556.mm.1	NM_008102.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1400014556.mm.1	NM_008102.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1400014556.mm.1	TC1400001930.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	437987	-	-