Mm00514996_m1

• Gene Symbol: Gclm
• Gene Name: glutamate-cysteine ligase, modifier subunit
• Gene Aliases: AI649393, Gcmc, Glclr
• Chromosome Location: Chr.3: 122245557 - 122267215 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Gclm
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008129.4	NP_032155.1	2 - 3	617		76
GenBank mRNA	AK028236.1	-	2 - 3	583		76
	AK172387.1	-	2 - 3	558		76
	AK176933.1	-	2 - 3			76
	BC132404.1	-	3 - 4	304	40130681	76
	BC138783.1	-	3 - 4	326	8861805	76
	CT010256.1	-	2 - 3	188		76
	U95053.1	-	2 - 3	228		76

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0300001244.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Gclm

Panther Classification:

Molecular Function -

ligase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

cysteine metabolic process
glutamate metabolic process
glutathione metabolic process
glutathione biosynthetic process
response to oxidative stress
apoptotic mitochondrial changes
positive regulation of glutamate-cysteine ligase activity
response to drug
negative regulation of neuron apoptotic process
regulation of catalytic activity
regulation of blood vessel size
response to nitrosative stress
regulation of mitochondrial depolarization
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

glutamate-cysteine ligase activity
enzyme regulator activity
glutamate-cysteine ligase catalytic subunit binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	436575	-	-