Mm00547106_m1

• Gene Symbol: Smurf1
• Gene Name: SMAD specific E3 ubiquitin protein ligase 1
• Gene Aliases: 4930431E10Rik, mKIAA1625
• Chromosome Location: Chr.5: 144876495 - 144965830 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Smurf1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001038627.1	NP_001033716.1	15 - 16	2084		77
	NM_029438.3	NP_083714.3	15 - 16	2084		77
GenBank mRNA	AK015264.1	-	11 - 12	1483		77
	AK034736.1	-	6 - 7	682		77
	AK122534.1	-	4 - 5	459		77
	AK154491.1	-	15 - 16	2085		77
	BC029097.1	-	15 - 16	2112	3660965	77

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0500003585.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Smurf1

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

protein polyubiquitination
positive regulation of defense response to virus by host
protein export from nucleus
transforming growth factor beta receptor signaling pathway
protein ubiquitination
cell differentiation
negative regulation of ossification
BMP signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
ubiquitin-dependent SMAD protein catabolic process
receptor catabolic process
protein localization to cell surface
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
protein targeting to vacuole involved in autophagy
mitophagy in response to mitochondrial depolarization
positive regulation of dendrite extension
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Function(s)

ubiquitin-protein transferase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
ubiquitin protein ligase activity
I-SMAD binding
R-SMAD binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0500032854.mm.1	TC0500003585.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500032854.mm.1	NM_001038627.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500032854.mm.1	NM_001038627.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500032854.mm.1	NM_029438.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500032854.mm.1	NM_029438.3	Refseq