Mm00599819_m1

• Gene Symbol: Esr2
• Gene Name: estrogen receptor 2 (beta)
• Gene Aliases: ER[b], ERbeta, Estrb
• Chromosome Location: Chr.12: 76120419 - 76177259 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Esr2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_010157.3	NP_034287.3	6 - 7	1488		71
GenBank mRNA	BC141075.1	-	5 - 6	1190	9055687	71
	BC145329.1	-	5 - 6	1190	9053885	71
	U81451.1	-	5 - 6	960		71

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1200001942.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Mus musculus, Mouse Androgen Panel, Mouse Estrogen Panel, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Esr2

Gene Ontology Categories:

Process(es)

negative regulation of transcription by RNA polymerase II
ovarian follicle development
behavioral fear response
neuron migration
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription by RNA polymerase II
brain development
learning or memory
negative regulation of cell population proliferation
hormone-mediated apoptotic signaling pathway
intracellular steroid hormone receptor signaling pathway
intracellular estrogen receptor signaling pathway
response to testosterone
regulation of cell population proliferation
positive regulation of apoptotic process
steroid hormone mediated signaling pathway
regulation of neuron apoptotic process
estrous cycle
positive regulation of epidermal growth factor receptor signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription by RNA polymerase II
negative regulation of behavior
negative regulation of smooth muscle cell proliferation
negative regulation of epithelial cell proliferation
positive regulation of DNA-binding transcription factor activity
Sertoli cell proliferation
uterus development
vagina development
negative regulation of cell death
prostate gland epithelium morphogenesis
epithelial cell maturation involved in prostate gland development
negative regulation of androgen receptor signaling pathway
positive regulation of ERK1 and ERK2 cascade
negative regulation of neuron death
negative regulation of feeding behavior
negative regulation of reactive oxygen species metabolic process

Function(s)

RNA polymerase II cis-regulatory region sequence-specific DNA binding
core promoter sequence-specific DNA binding
DNA binding
DNA-binding transcription factor activity
steroid hormone receptor activity
nuclear receptor activity
steroid binding
protein binding
zinc ion binding
lipid binding
enzyme binding
estrogen receptor activity
estrogen response element binding
hormone binding
peroxisome proliferator activated receptor binding
sequence-specific DNA binding
metal ion binding
estradiol binding
steroid hormone binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1200013320.mm.1	TC1200001942.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1200013320.mm.1	NM_010157.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1200013320.mm.1	NM_010157.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1200013320.mm.1	NM_207707.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1200013320.mm.1	NM_207707.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1200013320.mm.1	NR_104386.1	Refseq