Mm00627001_m1

• Gene Symbol: Chek1
• Gene Name: checkpoint kinase 1
• Gene Aliases: C85740, Chk1, rad27
• Chromosome Location: Chr.9: 36708482 - 36726658 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Chek1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_007691.5	NP_031717.2	6 - 7	731		145
GenBank mRNA	AF016583.1	-	5 - 6	640		145
	AK011258.1	-	6 - 7	675		145
	AK033179.1	-	6 - 7	701		145
	AK045336.1	-	6 - 7	673		145
	AK166675.1	-	6 - 7	732		145
	BC037613.1	-	5 - 6	444		145
	BC053394.1	-	6 - 7	667		146
	BC064445.1	-	5 - 6	1131		144
	BC100386.1	-	5 - 6	806	30481390	145

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0900002036.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Chek1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
G2/M transition of mitotic cell cycle
DNA repair
protein phosphorylation
cellular response to DNA damage stimulus
DNA damage induced protein phosphorylation
cell cycle
regulation of gene expression
regulation of double-strand break repair via homologous recombination
regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
negative regulation of G2/M transition of mitotic cell cycle
phosphorylation
peptidyl-threonine phosphorylation
G2 DNA damage checkpoint
histone H3-T11 phosphorylation
regulation of cell proliferation
negative regulation of mitotic nuclear division
regulation of mitotic centrosome separation
chromatin-mediated maintenance of transcription
negative regulation of DNA biosynthetic process
regulation of histone H3-K9 acetylation

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
histone kinase activity (H3-T11 specific)

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0900016900.mm.1	NM_007691.5.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016900.mm.1	NM_007691.5	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016900.mm.1	TC0900002036.mm.1	MTA TC