Mm00628112_m1

• Gene Symbol: Tlr3
• Gene Name: toll-like receptor 3
• Gene Aliases: AI957183
• Chromosome Location: Chr.8: 45395665 - 45411949 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Tlr3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_126166.4	NP_569054.2	2 - 3	280		95
GenBank mRNA	AK083977.1	-	2 - 3	281		95
	AK087739.1	-	1 - 2	102		95
	AK171438.1	-	2 - 3	263		95
	BC099937.1	-	2 - 3	318	30084049	95

More Information

Additional Information:

This assay is in the 5'UTR region of the AK083977.1, AK087739.1, BC099937.1, NM_126166.4 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Tlr3

Gene Ontology Categories:

Process(es)

microglial cell activation
positive regulation of cytokine production
positive regulation of protein phosphorylation
toll-like receptor signaling pathway
microglial cell activation involved in immune response
immune system process
regulation of dendritic cell cytokine production
MyD88-independent toll-like receptor signaling pathway
defense response
inflammatory response
signal transduction
I-kappaB phosphorylation
response to virus
positive regulation of type I interferon production
positive regulation of chemokine production
positive regulation of interferon-beta production
positive regulation of interleukin-12 production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of toll-like receptor signaling pathway
toll-like receptor 3 signaling pathway
positive regulation of type III interferon production
positive regulation of NF-kappaB import into nucleus
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to exogenous dsRNA
response to dsRNA
positive regulation of interferon-gamma biosynthetic process
positive regulation of chemokine biosynthetic process
innate immune response
positive regulation of interferon-alpha biosynthetic process
positive regulation of interferon-beta biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
positive regulation of inflammatory response
positive regulation of NF-kappaB transcription factor activity
defense response to virus
cellular response to exogenous dsRNA
extrinsic apoptotic signaling pathway
necroptotic signaling pathway

Function(s)

RNA binding
double-stranded RNA binding
receptor activity
transmembrane signaling receptor activity
protein binding
identical protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0800016529.mm.1	TC0800002146.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	362865	-	-