Mm00804775_gH

• Gene Symbol: Adrbk1
• Gene Name: adrenergic receptor kinase, beta 1
• Gene Aliases: Adrbk-1, Bark-1, GRK2, beta ARK, betaARK1
• Chromosome Location: Chr.19: 4285999 - 4306222 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Adrbk1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001290818.1	NP_001277747.1	10 - 11	1039		80
	NM_130863.2	NP_570933.1	11 - 12	1111		80
GenBank mRNA	AF333028.1	-	10 - 11	831		80
	AK155691.1	-	10 - 11	1040		80
	BC003196.1	-	10 - 11	827		80
	BC033272.1	-	9 - 10	1155		80
	BC053922.1	-	11 - 12	844	6309555	80

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1900000916.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Protein Kinase, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Adrbk1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

regulation of the force of heart contraction
desensitization of G-protein coupled receptor protein signaling pathway
negative regulation of the force of heart contraction by chemical signal
protein phosphorylation
response to oxidative stress
signal transduction
G-protein coupled receptor signaling pathway
tachykinin receptor signaling pathway
heart development
response to organic cyclic compound
phosphorylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
viral genome replication
receptor internalization
positive regulation of catecholamine secretion
termination of G-protein coupled receptor signaling pathway
follicle-stimulating hormone signaling pathway
negative regulation of G-protein coupled receptor protein signaling pathway
negative regulation of striated muscle contraction
viral entry into host cell
cardiac muscle contraction

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
G-protein coupled receptor kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Edg-2 lysophosphatidic acid receptor binding
beta-adrenergic receptor kinase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1900008006.mm.1	NM_130863.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1900008006.mm.1	TC1900000916.mm.1	MTA TC