Mm01136494_m1

• Gene Symbol: Pak1
• Gene Name: p21 protein (Cdc42/Rac)-activated kinase 1
• Gene Aliases: AW045634, PAK-1, Paka
• Chromosome Location: Chr.7: 97788047 - 97912381 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Pak1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011035.2	NP_035165.2	12 - 13	1443		68
GenBank mRNA	AF082077.1	-	12 - 13	1408		68
	AK077497.1	-	12 - 13	1408		68
	BC055740.1	-	9 - 10	1091		68
	BC060157.1	-	9 - 10	1091		68
	BC079838.1	-	12 - 13	1428		68
	BC145698.1	-	13 - 14	1367		68

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0700001362.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Pak1

Gene Ontology Categories:

Process(es)

response to hypoxia
positive regulation of protein phosphorylation
protein phosphorylation
exocytosis
apoptotic process
Rho protein signal transduction
regulation of mitotic cell cycle
neuromuscular junction development
metabolic process
response to organic substance
regulation of gene expression
phosphorylation
dendrite development
cell migration
amygdala development
signal transduction by protein phosphorylation
actin cytoskeleton organization
stress-activated protein kinase signaling cascade
actin cytoskeleton reorganization
activation of protein kinase activity
cellular response to insulin stimulus
regulation of actin cytoskeleton organization
positive regulation of peptidyl-serine phosphorylation
positive regulation of intracellular estrogen receptor signaling pathway
wound healing
regulation of apoptotic process
receptor clustering
regulation of MAPK cascade
positive regulation of JUN kinase activity
protein autophosphorylation
branching morphogenesis of an epithelial tube
neuron projection morphogenesis
positive regulation of stress fiber assembly
negative regulation of cell proliferation involved in contact inhibition
dendritic spine development
gamma-aminobutyric acid secretion, neurotransmission
glutamate secretion, neurotransmission
cellular response to organic cyclic compound
observational learning
regulation of long-term synaptic potentiation

Function(s)

nucleotide binding
catalytic activity
protein kinase activity
protein serine/threonine kinase activity
protein binding
collagen binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
Rac GTPase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0700011578.mm.1	TC0700001362.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0700011578.mm.1	NM_011035.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0700011578.mm.1	NM_011035.2	Refseq