Mm01149110_m1

• Gene Symbol: Gclc
• Gene Name: glutamate-cysteine ligase, catalytic subunit
• Gene Aliases: D9Wsu168e, GLCL-H, Ggcs-hs, Glclc
• Chromosome Location: Chr.9: 77754516 - 77794489 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Gclc
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_010295.2	NP_034425.1	1 - 2	424		60
GenBank mRNA	AK144339.1	-	1 - 2	425		60
	AK160876.1	-	1 - 2	184		60
	AK169676.1	-	1 - 2	397		60
	BC019374.1	-	1 - 2	181	4195425	60
	U85414.1	-	1 - 2	149		60
	U85498.1	-	1 - 2	149		60

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0900001038.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Mus musculus, 1700, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Gclc

Panther Classification:

Molecular Function -

ligase

Gene Ontology Categories:

Process(es)

cysteine metabolic process
glutamate metabolic process
glutathione metabolic process
glutathione biosynthetic process
response to oxidative stress
apoptotic mitochondrial changes
response to heat
response to xenobiotic stimulus
response to hormone
L-ascorbic acid metabolic process
negative regulation of protein ubiquitination
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
cell redox homeostasis
negative regulation of transcription, DNA-templated
response to arsenic-containing substance
regulation of blood vessel size
response to nitrosative stress
regulation of mitochondrial depolarization
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

nucleotide binding
magnesium ion binding
glutamate-cysteine ligase activity
ATP binding
glutamate binding
ligase activity
ADP binding
protein heterodimerization activity
coenzyme binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0900008130.mm.1	NM_010295.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900008130.mm.1	NM_010295.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0900008130.mm.1	TC0900001038.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0900008129.mm.1	NM_010295.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900008129.mm.1	NM_010295.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0900008129.mm.1	TC0900001038.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0900008128.mm.1	NM_010295.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900008128.mm.1	NM_010295.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0900008128.mm.1	TC0900001038.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0900008127.mm.1	NM_010295.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900008127.mm.1	NM_010295.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0900008127.mm.1	TC0900001038.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	323718	-	-