Mm01150868_m1

• Gene Symbol: Tirap
• Gene Name: toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
• Gene Aliases: AA407980, C130027E04Rik, Mal, Tlr4ap, Wyatt
• Chromosome Location: Chr.9: 35184391 - 35200291 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Tirap
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001177845.1	NP_001171316.1	2 - 3	231		67
	NM_001177846.1	NP_001171317.1	2 - 3	213		67
GenBank mRNA	AK036431.1	-	2 - 3	152		67
	AK080135.1	-	2 - 3	232		67
	BY740695.1	-	2 - 3	219		67

More Information

Additional Information:

This assay is in the 5'UTR region of the AK036431.1, AK080135.1, NM_001177845.1, NM_001177846.1 transcripts.

• Set Membership: Amplicon length less than or equal to 70, Mus musculus, Probe spans exons

Gene Ontology Categories:

Process(es)

immune system process
inflammatory response
signal transduction
cell surface receptor signaling pathway
I-kappaB kinase/NF-kappaB signaling
activation of JUN kinase activity
response to bacterium
myeloid cell differentiation
positive regulation of B cell proliferation
response to lipopolysaccharide
regulation of interferon-beta production
regulation of interleukin-15 production
positive regulation of interleukin-12 production
positive regulation of interleukin-15 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of toll-like receptor 2 signaling pathway
positive regulation of toll-like receptor 3 signaling pathway
positive regulation of toll-like receptor 4 signaling pathway
toll-like receptor 5 signaling pathway
TIRAP-dependent toll-like receptor 4 signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of growth of symbiont in host
innate immune response
regulation of innate immune response
positive regulation of innate immune response
positive regulation of interleukin-6 biosynthetic process
positive regulation of JNK cascade
defense response to Gram-positive bacterium
positive regulation of NF-kappaB transcription factor activity
positive regulation of ERK1 and ERK2 cascade
interleukin-1-mediated signaling pathway
3'-UTR-mediated mRNA stabilization
cellular response to bacterial lipopeptide
cellular response to lipoteichoic acid
positive regulation of neutrophil chemotaxis
positive regulation of protein homodimerization activity
positive regulation of chemokine (C-X-C motif) ligand 1 production
positive regulation of chemokine (C-X-C motif) ligand 2 production

Function(s)

protein kinase C binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
Toll-like receptor 4 binding
Toll-like receptor 2 binding
protein homodimerization activity
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0900016686.mm.1	NM_001177846.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016686.mm.1	NM_001177846.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016686.mm.1	NM_054096.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016686.mm.1	NM_054096.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016686.mm.1	TC0900002008.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0900016680.mm.1	NM_001177845.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016680.mm.1	NM_001177845.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016680.mm.1	NM_001177846.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016680.mm.1	NM_001177846.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016680.mm.1	NM_001177847.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016680.mm.1	NM_001177847.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016680.mm.1	NM_054096.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016680.mm.1	NM_054096.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016680.mm.1	TC0900002008.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0900016678.mm.1	NM_001177845.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016678.mm.1	NM_001177845.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016678.mm.1	NM_001177846.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016678.mm.1	NM_001177846.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016678.mm.1	NM_001177847.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016678.mm.1	NM_001177847.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016678.mm.1	NM_054096.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016678.mm.1	NM_054096.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016678.mm.1	TC0900002008.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0900016689.mm.1	NM_001177845.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016689.mm.1	NM_001177845.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016689.mm.1	TC0900002008.mm.1	MTA TC