Mm01150869_g1

• Gene Symbol: Tirap
• Gene Name: toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
• Gene Aliases: AA407980, C130027E04Rik, Mal, Tlr4ap, Wyatt
• Chromosome Location: Chr.9: 35184391 - 35200291 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Tirap
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001177845.1	NP_001171316.1	4 - 5	412		73
	NM_001177846.1	NP_001171317.1	4 - 5	394		73
	NM_001177847.1	NP_001171318.1	4 - 5	340		73
	NM_054096.2	NP_473437.2	4 - 5	404		73
GenBank mRNA	AF378130.1	-	4 - 5	313		73
	AF410784.1	-	3 - 4	236		73
	AK036431.1	-	4 - 5	333		73
	AK080135.1	-	4 - 5	413		73
	AK151117.1	-	4 - 5	342		73
	AK168494.1	-	4 - 5	332		73
	BC005584.1	-	1 - 2	70	3157913	73
	BY740695.1	-	4 - 5	400		73
	BY743490.1	-	4 - 5	340		73

More Information

Additional Information:

This assay is in the 5'UTR region of the AF378130.1, AF410784.1, AK036431.1, AK080135.1, AK151117.1, AK168494.1, BC005584.1, NM_001177845.1, NM_001177846.1, NM_001177847.1, NM_054096.2 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Tirap

Gene Ontology Categories:

Process(es)

immune system process
inflammatory response
signal transduction
cell surface receptor signaling pathway
I-kappaB kinase/NF-kappaB signaling
activation of JUN kinase activity
response to bacterium
myeloid cell differentiation
positive regulation of B cell proliferation
response to lipopolysaccharide
regulation of interferon-beta production
regulation of interleukin-15 production
positive regulation of interleukin-12 production
positive regulation of interleukin-15 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of toll-like receptor 2 signaling pathway
positive regulation of toll-like receptor 3 signaling pathway
positive regulation of toll-like receptor 4 signaling pathway
toll-like receptor 5 signaling pathway
TIRAP-dependent toll-like receptor 4 signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of growth of symbiont in host
innate immune response
regulation of innate immune response
positive regulation of innate immune response
positive regulation of interleukin-6 biosynthetic process
positive regulation of JNK cascade
defense response to Gram-positive bacterium
positive regulation of NF-kappaB transcription factor activity
positive regulation of ERK1 and ERK2 cascade
interleukin-1-mediated signaling pathway
3'-UTR-mediated mRNA stabilization
cellular response to bacterial lipopeptide
cellular response to lipoteichoic acid
positive regulation of neutrophil chemotaxis
positive regulation of protein homodimerization activity
positive regulation of chemokine (C-X-C motif) ligand 1 production
positive regulation of chemokine (C-X-C motif) ligand 2 production

Function(s)

protein kinase C binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
Toll-like receptor 4 binding
Toll-like receptor 2 binding
protein homodimerization activity
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0900016675.mm.1	NM_001177845.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016675.mm.1	NM_001177845.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016675.mm.1	NM_001177846.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016675.mm.1	NM_001177846.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016675.mm.1	NM_001177847.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016675.mm.1	NM_001177847.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016675.mm.1	NM_054096.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016675.mm.1	NM_054096.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0900016675.mm.1	TC0900002008.mm.1	MTA TC