Mm01170642_m1

• Gene Symbol: Pak2
• Gene Name: p21 protein (Cdc42/Rac)-activated kinase 2
• Gene Aliases: 5330420P17Rik, A130002K10Rik, AI836325, D16Ertd269e, PAK-2, mKIAA4182
• Chromosome Location: Chr.16: 32016290 - 32079342 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Pak2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_177326.3	NP_796300.1	10 - 11	1215		139
GenBank mRNA	AK037275.1	-	10 - 11	1217		139
	AY167030.1	-	9 - 10	941		139
	BC063068.1	-		1203		139
	BC086650.1	-	10 - 11	1146	6849008	139

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1600001497.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Protein Kinase, Mammalian Gene Collection, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Pak2

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

protein phosphorylation
apoptotic process
Rho protein signal transduction
regulation of mitotic cell cycle
metabolic process
phosphorylation
cell migration
peptidyl-serine phosphorylation
signal transduction by protein phosphorylation
actin cytoskeleton organization
stress-activated protein kinase signaling cascade
activation of protein kinase activity
regulation of growth
negative regulation of apoptotic process
regulation of MAPK cascade
protein autophosphorylation
positive regulation of peptidyl-tyrosine phosphorylation
dendritic spine development
positive regulation of protein tyrosine kinase activity
cellular response to organic cyclic compound
positive regulation of extrinsic apoptotic signaling pathway
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

Function(s)

nucleotide binding
catalytic activity
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
protein tyrosine kinase activator activity
identical protein binding
Rac GTPase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1600012290.mm.1	NM_177326.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1600012290.mm.1	TC1600001497.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	300961	-	-