Mm01197781_m1

• Gene Symbol: Rabgef1
• Gene Name: RAB guanine nucleotide exchange factor (GEF) 1
• Gene Aliases: Rab5ef, Rabex5, Rin2
• Chromosome Location: Chr.5: 130171791 - 130214342 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Rabgef1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001199059.1	NP_001185988.1	4 - 5	598		134
	NM_019983.2	NP_064367.1	3 - 4	743		134
GenBank mRNA	AF093590.1	-	4 - 5	574		134
	AK044568.1	-	3 - 4	763		134
	AK146734.1	-	4 - 5	548		134
	BC018229.1	-	3 - 4	743	4507477	134

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect transcript(s) from off target gene(s). Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Rabgef1

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
negative regulation of leukocyte migration
protein targeting to membrane
transport
endocytosis
protein transport
protein ubiquitination
negative regulation of mast cell activation
negative regulation of mast cell degranulation
positive regulation of GTPase activity
negative regulation of Ras protein signal transduction
negative regulation of receptor-mediated endocytosis
negative regulation of inflammatory response
regulation of Fc receptor mediated stimulatory signaling pathway
negative regulation of interleukin-6 secretion
negative regulation of Kit signaling pathway

Function(s)

DNA binding
protein binding
zinc ion binding
Rab guanyl-nucleotide exchange factor activity
Rab GTPase binding
metal ion binding
ubiquitin protein ligase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0500013793.mm.1	TC0500001526.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500013793.mm.1	NM_001199059.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013793.mm.1	NM_001199059.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013793.mm.1	NM_019983.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013793.mm.1	NM_019983.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013792.mm.1	TC0500001526.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500013792.mm.1	NM_001199059.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013792.mm.1	NM_001199059.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013792.mm.1	NM_019983.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013792.mm.1	NM_019983.2	Refseq