Mm01204471_g1

• Gene Symbol: Serpine1
• Gene Name: serine (or cysteine) peptidase inhibitor, clade E, member 1
• Gene Aliases: PAI-1, PAI1, Planh1
• Chromosome Location: Chr.5: 137061504 - 137072272 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Serpine1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008871.2	NP_032897.2	6 - 7	1140		64
GenBank mRNA	BC054091.1	-	6 - 7	1137	30021925	64
	GQ872458.1	-	5 - 6	995		64
	GQ872459.1	-	5 - 6	995		64
	M33960.1	-	6 - 7	1126		64

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0500003431.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Serpine1

Gene Ontology Categories:

Process(es)

female gonad development
negative regulation of peptidase activity
regulation of signaling receptor activity
positive regulation of gene expression
negative regulation of gene expression
negative regulation of plasminogen activation
negative regulation of endopeptidase activity
negative regulation of smooth muscle cell migration
positive regulation of blood coagulation
negative regulation of cell migration
positive regulation of interleukin-8 production
negative regulation of cell adhesion mediated by integrin
positive regulation of leukotriene production involved in inflammatory response
wound healing
regulation of cell population proliferation
regulation of angiogenesis
positive regulation of angiogenesis
positive regulation of fibroblast proliferation
positive regulation of receptor-mediated endocytosis
positive regulation of inflammatory response
positive regulation of coagulation
defense response to Gram-negative bacterium
positive regulation of keratinocyte migration
negative regulation of fibrinolysis
negative regulation of vascular wound healing
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to xenobiotic stimulus
cellular response to transforming growth factor beta stimulus
positive regulation of monocyte chemotaxis
positive regulation of calcium ion import
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of smooth muscle cell-matrix adhesion
negative regulation of endothelial cell apoptotic process

Function(s)

protease binding
serine-type endopeptidase inhibitor activity
signaling receptor binding
protein binding
peptidase inhibitor activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0500031098.mm.1	TC0500003431.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500031098.mm.1	NM_008871.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500031098.mm.1	NM_008871.2	Refseq