Mm01218949_g1

• Gene Symbol: Mapk8
• Gene Name: mitogen-activated protein kinase 8
• Gene Aliases: AI849689, JNK, JNK1, Prkm8, SAPK1
• Chromosome Location: Chr.14: 33377898 - 33447214 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Mapk8
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_016700.4	NP_057909.1	9 - 10	1191		87
GenBank mRNA	AB005663.1	-	8 - 9	1024		87
	AB206575.1	-	8 - 9	966		87
	AB219977.1	-	8 - 9	1000		87
	AK043102.1	-	9 - 10	1191		87
	AK139498.1	-	9 - 10	1179		87
	BC053027.1	-	9 - 10	1161	5694771	87

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1400001711.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Protein Kinase, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Mapk8

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

ossification
regulation of transcription, DNA-templated
protein phosphorylation
inflammatory response
response to osmotic stress
signal transduction
JNK cascade
JUN phosphorylation
response to heat
response to UV
regulation of gene expression
positive regulation of gene expression
phosphorylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
positive regulation of cell migration
regulation of histone deacetylation
positive regulation of microtubule polymerization
neuron projection development
positive regulation of cyclase activity
negative regulation of protein binding
regulation of protein localization
response to hydrogen peroxide
regulation of circadian rhythm
negative regulation of apoptotic process
positive regulation of DNA replication
response to cadmium ion
determination of dorsal identity
rhythmic process
positive regulation of protein metabolic process
cellular response to hydrogen peroxide
cellular response to lipopolysaccharide
cellular response to nitric oxide
positive regulation of deacetylase activity
type B pancreatic cell apoptotic process
neuronal stem cell population maintenance
programmed necrotic cell death
positive regulation of determination of dorsal identity
positive regulation of apoptotic signaling pathway

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
JUN kinase activity
MAP kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
enzyme binding
histone deacetylase regulator activity
histone deacetylase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1400013328.mm.1	NM_016700.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1400013328.mm.1	NM_016700.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1400013328.mm.1	TC1400001711.mm.1	MTA TC