Mm01222247_m1 Best Coverage

• Gene Symbol: Ikbkb
• Gene Name: inhibitor of kappaB kinase beta
• Gene Aliases: AI132552, IKK-2, IKK-beta, IKK2, IKK[b], IKKbeta
• Chromosome Location: Chr.8: 22659205 - 22706585 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Ikbkb
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001159774.1	NP_001153246.1	4 - 5	452		63
	NM_010546.2	NP_034676.1	4 - 5	452		63
GenBank mRNA	AF026524.1	-	3 - 4	320		63
	AF088910.1	-	4 - 5	512		63
	AK011359.1	-	4 - 5	419		63
	AK086442.1	-	4 - 5	448		63
	AK139972.1	-	4 - 5	410		63
	AK144048.1	-	4 - 5	429		63
	AK144603.1	-	4 - 5	445		63
	AK150884.1	-	4 - 5	404		63
	AK151888.1	-	4 - 5	404		63
	AK151955.1	-	4 - 5	404		63
	AK153151.1	-	4 - 5	404		63
	AK155587.1	-	4 - 5	404		63
	AK156294.1	-	4 - 5	410		63
	AK182153.1	-	1 - 2	92		63
	AK201390.1	-	2 - 3	230		63
	BC004772.1	-	4 - 5	390		63
	BC037723.1	-	4 - 5	424	4482634	63

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0800001874.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Protein Kinase, Mammalian Gene Collection, Recommended Assay, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Ikbkb

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

B cell homeostasis
protein phosphorylation
I-kappaB phosphorylation
positive regulation of cell proliferation
positive regulation of sodium ion transport
phosphorylation
signal transduction by protein phosphorylation
neuron projection development
serine phosphorylation of STAT protein
positive regulation of transcription from RNA polymerase II promoter
positive regulation of NF-kappaB transcription factor activity
cellular response to tumor necrosis factor
positive regulation of neuron death
positive regulation of cation channel activity

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein binding
ATP binding
IkappaB kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
protein homodimerization activity
protein heterodimerization activity
scaffold protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0800014840.mm.1	NM_001159774.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0800014840.mm.1	NM_001159774.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0800014840.mm.1	NM_010546.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0800014840.mm.1	NM_010546.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0800014840.mm.1	TC0800001874.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	827078	-	-