Mm01240112_g1

• Gene Symbol: Dnmt3b
• Gene Name: DNA methyltransferase 3B
• Gene Aliases: MmuIIIB
• Chromosome Location: Chr.2: 153649165 - 153687730 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Dnmt3b
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001003960.4	NP_001003960.2	18 - 19	2367		68
	NM_001003961.4	NP_001003961.2	19 - 20	2427		68
	NM_001003963.4	NP_001003963.2	19 - 20	2427		68
	NM_001122997.2	NP_001116469.1	18 - 19	2315		68
	NM_001271744.1	NP_001258673.1	18 - 19	2312		68
	NM_001271745.1	NP_001258674.1	17 - 18	2252		68
	NM_001271746.1	NP_001258675.1	18 - 19	2312		68
	NM_001271747.1	NP_001258676.1	17 - 18	2252		68
	NM_010068.5	NP_034198.3	18 - 19	2367		68
GenBank mRNA	AF068626.2	-	19 - 20	2282		68
	AF068627.2	-	18 - 19	2222		68
	AF068628.2	-	18 - 19	2222		68
	AF151969.1	-	19 - 20	2425		68
	AF151970.1	-	18 - 19	2365		68
	AF151971.1	-	18 - 19	2365		68
	AF151972.1	-	19 - 20	2425		68
	AF151973.1	-	18 - 19	2310		68
	AF151974.1	-	17 - 18	2250		68
	AF151975.1	-	18 - 19	2310		68
	AF151976.1	-	17 - 18	2250		68
	AY078427.1	-	19 - 20	2282		68
	BC105677.1	-	18 - 19	2147	40048574	68
	BC105922.1	-	18 - 19	2147	40048584	68

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0200002318.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Dnmt3b

Panther Classification:

Molecular Function -

DNA methyltransferase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA methylation
methylation-dependent chromatin silencing
regulation of gene expression by genetic imprinting
DNA methylation on cytosine within a CG sequence
positive regulation of gene expression
protein complex localization
methylation
positive regulation of neuron differentiation
negative regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
S-adenosylhomocysteine metabolic process
S-adenosylmethioninamine metabolic process
positive regulation of histone H3-K4 methylation
negative regulation of histone H3-K9 methylation
inactivation of X chromosome by DNA methylation
cellular response to amino acid stimulus
C-5 methylation of cytosine

Function(s)

DNA binding
chromatin binding
transcription corepressor activity
DNA (cytosine-5-)-methyltransferase activity
protein binding
methyltransferase activity
transferase activity
histone deacetylase binding
unmethylated CpG binding
metal ion binding
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0200018257.mm.1	NM_001003960.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018257.mm.1	NM_001003961.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018257.mm.1	NM_001003963.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018257.mm.1	NM_001122997.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018257.mm.1	NM_001271744.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018257.mm.1	NM_001271745.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018257.mm.1	NM_001271746.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018257.mm.1	NM_001271747.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018257.mm.1	NM_010068.5	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018257.mm.1	TC0200002318.mm.1	MTA TC