Mm01240113_m1 Best Coverage

• Gene Symbol: Dnmt3b
• Gene Name: DNA methyltransferase 3B
• Gene Aliases: MmuIIIB
• Chromosome Location: Chr.2: 153649165 - 153687730 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Dnmt3b
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001003960.4	NP_001003960.2	19 - 20	2518		83
	NM_001003961.4	NP_001003961.2	20 - 21	2578		83
	NM_001003963.4	NP_001003963.2	20 - 21	2578		83
	NM_001122997.2	NP_001116469.1	19 - 20	2466		83
	NM_001271744.1	NP_001258673.1	19 - 20	2463		83
	NM_001271745.1	NP_001258674.1	18 - 19	2403		83
	NM_001271746.1	NP_001258675.1	19 - 20	2463		83
	NM_001271747.1	NP_001258676.1	18 - 19	2403		83
	NM_010068.5	NP_034198.3	19 - 20	2518		83
GenBank mRNA	AF068626.2	-	20 - 21	2433		83
	AF068627.2	-	19 - 20	2373		83
	AF068628.2	-	19 - 20	2373		83
	AF151969.1	-	20 - 21	2576		83
	AF151970.1	-	19 - 20	2516		83
	AF151971.1	-	19 - 20	2516		83
	AF151972.1	-	20 - 21	2576		83
	AF151973.1	-	19 - 20	2461		83
	AF151974.1	-	18 - 19	2401		83
	AF151975.1	-	19 - 20	2461		83
	AF151976.1	-	18 - 19	2401		83
	AY078427.1	-	20 - 21	2433		83
	BC105677.1	-	19 - 20	2298	40048574	83
	BC105922.1	-	19 - 20	2298	40048584	83

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0200002318.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Recommended Assay, Mus musculus, Mouse Stem Cell Pluripotency, Inventoried, Mouse_Stem_Cell, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Dnmt3b

Panther Classification:

Molecular Function -

DNA methyltransferase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA methylation
methylation-dependent chromatin silencing
regulation of gene expression by genetic imprinting
DNA methylation on cytosine within a CG sequence
positive regulation of gene expression
protein complex localization
methylation
positive regulation of neuron differentiation
negative regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
S-adenosylhomocysteine metabolic process
S-adenosylmethioninamine metabolic process
positive regulation of histone H3-K4 methylation
negative regulation of histone H3-K9 methylation
inactivation of X chromosome by DNA methylation
cellular response to amino acid stimulus
C-5 methylation of cytosine

Function(s)

DNA binding
chromatin binding
transcription corepressor activity
DNA (cytosine-5-)-methyltransferase activity
protein binding
methyltransferase activity
transferase activity
histone deacetylase binding
unmethylated CpG binding
metal ion binding
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0200018258.mm.1	NM_001003960.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018258.mm.1	NM_001003961.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018258.mm.1	NM_001003963.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018258.mm.1	NM_001122997.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018258.mm.1	NM_001271744.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018258.mm.1	NM_001271745.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018258.mm.1	NM_001271746.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018258.mm.1	NM_001271747.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018258.mm.1	NM_010068.5	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018258.mm.1	TC0200002318.mm.1	MTA TC