Mm01246070_m1

• Gene Symbol: Hdac5
• Gene Name: histone deacetylase 5
• Gene Aliases: AI426555, Hdac4, mHDA1, mKIAA0600
• Chromosome Location: Chr.11: 102195747 - 102230186 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Hdac5
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001077696.1	NP_001071164.1	11 - 12	1732		81
	NM_001284248.1	NP_001271177.1	13 - 14	2244		81
	NM_001284249.1	NP_001271178.1	12 - 13	1841		81
	NM_001284250.1	NP_001271179.1	11 - 12	1729		81
	NM_010412.3	NP_034542.3	11 - 12	1729		81
GenBank mRNA	AK122325.2	-	6 - 7	768		81
	AK139202.1	-	12 - 13	1815		81
	AK145972.1	-	11 - 12	1695		81
	AK146483.1	-	11 - 12	1668		81
	AK155335.1	-	11 - 12	1703		81
	AK156008.1	-	5 - 6	2566		81
	AK157159.1	-	5 - 6	2566		81
	BC023309.1	-	2 - 3			81
	BC049926.1	-	11 - 12			81
	BC058554.1	-	13 - 14	2196		81
	BC060609.1	-	10 - 11	1523	5720438	81

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100003829.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Hdac5

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
osteoblast development
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein deacetylation
inflammatory response
nervous system development
heart development
negative regulation of gene expression
regulation of myotube differentiation
negative regulation of myotube differentiation
chromatin modification
histone deacetylation
B cell differentiation
multicellular organismal response to stress
regulation of gene expression, epigenetic
B cell activation
response to cocaine
response to drug
regulation of protein binding
negative regulation of osteoblast differentiation
negative regulation of striated muscle tissue development
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of skeletal muscle fiber development
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of striated muscle cell differentiation
renal tubule morphogenesis
cellular response to fluid shear stress
negative regulation of cell migration involved in sprouting angiogenesis
positive regulation of neural precursor cell proliferation
positive regulation of stem cell proliferation

Function(s)

RNA polymerase III transcription factor binding
core promoter sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
chromatin binding
transcription corepressor activity
histone deacetylase activity
protein kinase C binding
protein binding
transcription factor binding
hydrolase activity
protein kinase binding
histone deacetylase activity (H3-K14 specific)
NAD-dependent histone deacetylase activity (H3-K14 specific)
histone deacetylase activity (H3-K9 specific)
protein deacetylase activity
histone deacetylase activity (H4-K16 specific)
histone deacetylase binding
transcription regulatory region DNA binding
metal ion binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
NAD-dependent histone deacetylase activity (H4-K16 specific)
repressing transcription factor binding
NAD-dependent histone deacetylase activity (H3-K18 specific)

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100035544.mm.1	NM_001077696.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100035544.mm.1	NM_001077696.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100035544.mm.1	NM_001284248.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100035544.mm.1	NM_001284249.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100035544.mm.1	NM_001284250.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100035544.mm.1	NM_010412.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100035544.mm.1	NM_010412.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1100035544.mm.1	TC1100003829.mm.1	MTA TC