Mm01246513_m1

• Gene Symbol: Itch
• Gene Name: itchy, E3 ubiquitin protein ligase
• Gene Aliases: 6720481N21Rik, 8030492O04Rik, A130065M08, AIP4, C230047C07Rik
• Chromosome Location: Chr.2: 155133379 - 155226855 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Itch
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001243712.1	NP_001230641.1	1 - 2	103		74
	NM_008395.3	NP_032421.2	1 - 2	103		74
GenBank mRNA	AK020167.1	-	1 - 2	46		74
	AK037940.1	-	1 - 2	53		74
	AK141800.1	-	1 - 2	60		74
	AK163006.1	-	1 - 2	76		74
	BC048489.1	-	1 - 2	49		74
	BC062934.1	-	1 - 2	52	30535756	74
	CJ122836.1	-	1 - 2	103		74
	CN714704.1	-	1 - 2	65		74

More Information

Additional Information:

This assay is in the 5'UTR region of the BC062934.1, NM_001243712.1, NM_008395.3 transcripts.

• Set Membership: Amplicon length between 71 and 85, Mammalian Gene Collection, Mus musculus, Inventoried, Probe spans exons

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

protein polyubiquitination
immune system process
positive regulation of T cell anergy
ubiquitin-dependent protein catabolic process
apoptotic process
protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
protein K29-linked ubiquitination
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
innate immune response
positive regulation of protein catabolic process
negative regulation of JNK cascade
negative regulation of alpha-beta T cell proliferation
negative regulation of defense response to virus
defense response to virus
protein K63-linked ubiquitination
protein K48-linked ubiquitination
regulation of protein deubiquitination

Function(s)

ubiquitin-protein transferase activity
protein binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
ribonucleoprotein complex binding
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
CXCR chemokine receptor binding
ubiquitin protein ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0200018762.mm.1	NM_001243712.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018762.mm.1	NM_001243712.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018762.mm.1	NM_008395.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018762.mm.1	NM_008395.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018762.mm.1	TC0200002359.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0200018772.mm.1	NM_001243712.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018772.mm.1	NM_001243712.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018772.mm.1	TC0200002359.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0200018770.mm.1	NM_001243712.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018770.mm.1	NM_001243712.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018770.mm.1	NM_008395.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018770.mm.1	NM_008395.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018770.mm.1	TC0200002359.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0200018774.mm.1	NM_001243712.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018774.mm.1	NM_001243712.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018774.mm.1	NM_008395.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018774.mm.1	NM_008395.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018774.mm.1	TC0200002359.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0200018766.mm.1	NM_001243712.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018766.mm.1	NM_001243712.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018766.mm.1	NM_008395.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018766.mm.1	NM_008395.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0200018766.mm.1	TC0200002359.mm.1	MTA TC