Mm01248084_m1

• Gene Symbol: Ptpn1
• Gene Name: protein tyrosine phosphatase, non-receptor type 1
• Gene Aliases: PTP-1B, PTP-HA2, PTP1B
• Chromosome Location: Chr.2: 167932303 - 167979385 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Ptpn1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011201.3	NP_035331.3	2 - 3	319		113
GenBank mRNA	AK149979.1	-	2 - 3	275		113
	AK150322.1	-	2 - 3	275		113
	AK151371.1	-	2 - 3	232		113
	AK153088.1	-	2 - 3	258		113
	AK156281.1	-	2 - 3	280		113
	AK157431.1	-	2 - 3	320		113
	AK165567.1	-	2 - 3	284		113
	AK165949.1	-	3 - 4	399		113
	AK166020.1	-	2 - 3	275		113
	AK168772.1	-	2 - 3	274		113
	AK170620.1	-	2 - 3	275		113
	AK171380.1	-	2 - 3	275		113
	AK172206.1	-	3 - 4	392		113
	AK185938.1	-	1 - 2	26		113
	BC010191.1	-	2 - 3	237	3156854	113

More Information

Additional Information:

This assay is in the 5'UTR region of the AK172206.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Protein Phosphatase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Ptpn1

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

protein dephosphorylation
activation of JUN kinase activity
insulin receptor signaling pathway
regulation of signal transduction
dephosphorylation
regulation of endocytosis
negative regulation of vascular endothelial growth factor receptor signaling pathway
endoplasmic reticulum unfolded protein response
actin cytoskeleton reorganization
regulation of intracellular protein transport
response to endoplasmic reticulum stress
peptidyl-tyrosine dephosphorylation
platelet-derived growth factor receptor-beta signaling pathway
IRE1-mediated unfolded protein response
negative regulation of MAP kinase activity
regulation of insulin receptor signaling pathway
positive regulation of protein tyrosine kinase activity
negative regulation of ERK1 and ERK2 cascade
regulation of hepatocyte growth factor receptor signaling pathway
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
negative regulation of PERK-mediated unfolded protein response
peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity
positive regulation of receptor catabolic process

Function(s)

phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
insulin receptor binding
zinc ion binding
hydrolase activity
phosphatase activity
enzyme binding
protein kinase binding
receptor tyrosine kinase binding
poly(A) RNA binding
ephrin receptor binding
protein phosphatase 2A binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0200021431.mm.1	NM_011201.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200021431.mm.1	NM_011201.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0200021431.mm.1	TC0200002602.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0200021430.mm.1	NM_011201.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200021430.mm.1	NM_011201.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0200021430.mm.1	TC0200002602.mm.1	MTA TC