Mm01254075_m1

• Gene Symbol: Nck2
• Gene Name: non-catalytic region of tyrosine kinase adaptor protein 2
• Gene Aliases: 4833426I10Rik, Grb4, NCKbeta, Nck-2
• Chromosome Location: Chr.1: 43445749 - 43570518 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Nck2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_010879.3	NP_035009.3	1 - 2	279		59
GenBank mRNA	AK014949.1	-	1 - 2	272		59
	AK051665.1	-	1 - 2	279		59

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0100000323.mm.1

Additional Information:

This assay is in the 5'UTR region of the AK051665.1, NM_010879.3 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Nck2

Gene Ontology Categories:

Process(es)

immunological synapse formation
regulation of translation
actin filament organization
cell migration
lamellipodium assembly
positive regulation of actin filament polymerization
negative regulation of peptidyl-serine phosphorylation
positive regulation of translation in response to endoplasmic reticulum stress
positive regulation of T cell proliferation
positive regulation of transcription by RNA polymerase II
ephrin receptor signaling pathway
dendritic spine development
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
negative regulation of PERK-mediated unfolded protein response
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Function(s)

protein-containing complex binding
scaffold protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0100002396.mm.1	TC0100000323.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0100002396.mm.1	NM_010879.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0100002396.mm.1	NM_010879.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0100002401.mm.1	TC0100000323.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0100002401.mm.1	NM_010879.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0100002401.mm.1	NM_010879.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0100002403.mm.1	TC0100000323.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0100002403.mm.1	NM_010879.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0100002403.mm.1	NM_010879.3	Refseq

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	369149	-	-