Mm01297293_m1

• Gene Symbol: Il6st
• Gene Name: interleukin 6 signal transducer
• Gene Aliases: 5133400A03Rik, AA389424, BB405851, CD130, D13Ertd699e, gp130
• Chromosome Location: Chr.13: 112464070 - 112506860 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Il6st
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_010560.3	NP_034690.3	1 - 2	181		62
GenBank mRNA	BC020454.1	-	1 - 2	135		62
	BC058679.1	-	1 - 2	142	6834623	62
	CJ177012.1	-	1 - 2	183		62

More Information

Additional Information:

This assay is in the 5'UTR region of the BC058679.1, NM_010560.3 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Mus musculus, 1700, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Il6st

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

glycogen metabolic process
triglyceride mobilization
signal transduction
positive regulation of cell proliferation
regulation of Notch signaling pathway
positive regulation of smooth muscle cell migration
cytokine-mediated signaling pathway
response to cytokine
oncostatin-M-mediated signaling pathway
positive regulation of T cell proliferation
positive regulation of tyrosine phosphorylation of Stat1 protein
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of osteoblast differentiation
positive regulation of astrocyte differentiation
leukemia inhibitory factor signaling pathway
negative regulation of cytosolic calcium ion concentration
interleukin-6-mediated signaling pathway
negative regulation of interleukin-6-mediated signaling pathway
interleukin-27-mediated signaling pathway
ciliary neurotrophic factor-mediated signaling pathway

Function(s)

cytokine receptor activity
ciliary neurotrophic factor receptor activity
interleukin-6 receptor activity
interleukin-11 receptor activity
leukemia inhibitory factor receptor activity
oncostatin-M receptor activity
ciliary neurotrophic factor receptor binding
interleukin-6 receptor binding
protein binding
growth factor binding
interleukin-11 binding
interleukin-6 binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1300007976.mm.1	NM_010560.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1300007976.mm.1	NM_010560.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1300007976.mm.1	TC1300001265.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1300007974.mm.1	NM_010560.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1300007974.mm.1	NM_010560.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1300007974.mm.1	TC1300001265.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1300007981.mm.1	NM_010560.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1300007981.mm.1	NM_010560.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1300007981.mm.1	TC1300001265.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	647028	-	-