Mm01299954_m1

• Gene Symbol: Pdpk1
• Gene Name: 3-phosphoinositide dependent protein kinase 1
• Gene Aliases: Pdk1
• Chromosome Location: Chr.17: 24073680 - 24150922 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Pdpk1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001080773.2	NP_001074242.1	9 - 10	1090		158
	NM_001286662.1	NP_001273591.1	9 - 10	1008		158
	NM_011062.4	NP_035192.2	9 - 10	1090		158
GenBank mRNA	AF086625.1	-	9 - 10	1056		158
	AF126294.1	-	9 - 10	1031		158
	AK147149.1	-	9 - 10	1082		158
	AK147835.1	-	9 - 10	1065		158
	AK149162.1	-	9 - 10	1024		158
	AK149289.1	-	9 - 10	1048		158
	AK162677.1	-	9 - 10	1050		158
	AK165564.1	-	9 - 10	1027		158
	AY062008.1	-	9 - 10	986		158
	BC146001.1	-	9 - 10	1027	40131304	158
	BC146003.1	-	9 - 10	1027	40131306	158

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1700001615.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Pdpk1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

type B pancreatic cell development
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
negative regulation of protein kinase activity
hyperosmotic response
signal transduction
epidermal growth factor receptor signaling pathway
positive regulation of phospholipase activity
regulation of endothelial cell migration
negative regulation of cardiac muscle cell apoptotic process
phosphorylation
cell migration
peptidyl-threonine phosphorylation
calcium-mediated signaling
negative regulation of transforming growth factor beta receptor signaling pathway
activation of protein kinase B activity
cellular response to insulin stimulus
negative regulation of toll-like receptor signaling pathway
regulation of I-kappaB kinase/NF-kappaB signaling
regulation of mast cell degranulation
focal adhesion assembly
positive regulation of release of sequestered calcium ion into cytosol
cellular response to epidermal growth factor stimulus
positive regulation of establishment of protein localization to plasma membrane
extrinsic apoptotic signaling pathway

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
3-phosphoinositide-dependent protein kinase activity
insulin receptor binding
protein binding
ATP binding
phospholipase activator activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
phospholipase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1700014177.mm.1	NM_001080773.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014177.mm.1	NM_001286662.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014177.mm.1	NM_011062.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014177.mm.1	NM_011062.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1700014177.mm.1	TC1700001615.mm.1	MTA TC