Mm01303209_m1

• Gene Symbol: Cdkn1a
• Gene Name: cyclin-dependent kinase inhibitor 1A (P21)
• Gene Aliases: CAP20, CDKI, CIP1, Cdkn1, P21, SDI1, Waf1, mda6, p21Cip1, p21WAF
• Chromosome Location: Chr.17: 29090986 - 29100722 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Cdkn1a
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_007669.4	NP_031695.1	1 - 2	94		62
GenBank mRNA	AK007630.1	-	1 - 2	92		62
	AK089093.1	-	1 - 2	92		62
	AK139306.1	-	1 - 2	95		62
	AK149910.1	-	1 - 2	95		62
	AK170467.1	-	1 - 2	95		62
	BC002043.1	-	1 - 2	47	3495942	62
	U24173.1	-	1 - 2	85		62

More Information

Additional Information:

This assay is in the 5'UTR region of the AK007630.1, AK089093.1, AK139306.1, AK149910.1, AK170467.1, BC002043.1, NM_007669.4, U24173.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Mus musculus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Cdkn1a

Panther Classification:

Molecular Function -

kinase inhibitor

Gene Ontology Categories:

Process(es)

regulation of cyclin-dependent protein serine/threonine kinase activity
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
protein phosphorylation
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
cell cycle
cell cycle arrest
regulation of mitotic cell cycle
negative regulation of cell proliferation
response to UV
negative regulation of gene expression
negative regulation of cell growth
positive regulation of B cell proliferation
cellular response to extracellular stimulus
regulation of protein import into nucleus, translocation
negative regulation of phosphorylation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of apoptotic process
positive regulation of programmed cell death
negative regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of protein kinase activity
positive regulation of fibroblast proliferation
regulation of cell cycle
cellular response to ionizing radiation
cellular response to UV-B
mitotic cell cycle arrest
signal transduction by p53 class mediator
cellular senescence
negative regulation of G1/S transition of mitotic cell cycle
regulation of DNA biosynthetic process
positive regulation of reactive oxygen species metabolic process

Function(s)

protein kinase inhibitor activity
cyclin-dependent protein serine/threonine kinase inhibitor activity
protein binding
cyclin-dependent protein kinase activating kinase activity
cyclin binding
ubiquitin protein ligase binding
protein complex binding
metal ion binding