Mm01307300_m1

• Gene Symbol: Dab2
• Gene Name: disabled 2, mitogen-responsive phosphoprotein
• Gene Aliases: 5730435J12Rik, AA960054, AI957090, D15Wsu122e, D630005B22Rik, Doc-2, Doc2, p96
• Chromosome Location: Chr.15: 6299788 - 6440715 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Dab2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_023118.5	NP_075607.2	9 - 10	974		145
GenBank mRNA	AK154716.1	-	9 - 10	958		145
	CD348957.1	-	7 - 8	497		145
	U18869.1	-	9 - 10	907		145

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1500000031.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Dab2

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

cell morphogenesis involved in differentiation
in utero embryonic development
positive regulation of receptor recycling
positive regulation of protein phosphorylation
transport
endocytosis
receptor-mediated endocytosis
pinocytosis
apoptotic process
activation of JUN kinase activity
multicellular organism development
endoderm development
excretion
positive regulation of epithelial to mesenchymal transition
positive regulation of pathway-restricted SMAD protein phosphorylation
negative regulation of neuron projection development
protein transport
Wnt signaling pathway
cell differentiation
negative regulation of cell growth
positive regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of protein binding
positive regulation of aldosterone biosynthetic process
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of transcription elongation from RNA polymerase II promoter
leading edge cell differentiation
negative regulation of apoptotic process
positive regulation of cell adhesion
positive regulation of endocytosis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
clathrin coat assembly
response to steroid hormone
negative regulation of epithelial cell proliferation
positive regulation of SMAD protein import into nucleus
negative regulation of androgen receptor signaling pathway
negative regulation of ERK1 and ERK2 cascade
cellular response to epidermal growth factor stimulus
cellular response to transforming growth factor beta stimulus
negative regulation of canonical Wnt signaling pathway
positive regulation of substrate adhesion-dependent cell spreading
negative regulation of protein localization to plasma membrane
positive regulation of Wnt signaling pathway, planar cell polarity pathway
regulation of Rho-dependent protein serine/threonine kinase activity
positive regulation of clathrin-mediated endocytosis
positive regulation of early endosome to late endosome transport
positive regulation of aldosterone secretion
positive regulation of integrin-mediated signaling pathway
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

integrin binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
protein C-terminus binding
clathrin binding
phosphatidylinositol binding
AP-2 adaptor complex binding
clathrin adaptor activity
cargo receptor activity
SMAD binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1500000252.mm.1	NM_023118.5.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500000252.mm.1	NM_023118.5	Refseq
Affymetrix Mouse Clariom S Array	PSR1500000252.mm.1	TC1500000031.mm.1	MTA TC