Mm01319526_g1

• Gene Symbol: Apex1
• Gene Name: apurinic/apyrimidinic endonuclease 1
• Gene Aliases: APE, Apex, HAP1, Ref-1
• Chromosome Location: Chr.14: 50924944 - 50927188 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Apex1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_009687.2	NP_033817.1	1 - 2	86		62
GenBank mRNA	BC052401.1	-	1 - 2	57	5715485	62

More Information

Additional Information:

This assay is in the 5'UTR region of the BC052401.1, NM_009687.2 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Apex1

Gene Ontology Categories:

Process(es)

DNA repair
base-excision repair
DNA recombination
transcription, DNA-templated
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
aging
negative regulation of smooth muscle cell migration
regulation of mRNA stability
cell redox homeostasis
positive regulation of DNA repair
oxidation-reduction process
cellular response to hydrogen peroxide
DNA demethylation
nucleic acid phosphodiester bond hydrolysis
RNA phosphodiester bond hydrolysis, endonucleolytic
positive regulation of G1/S transition of mitotic cell cycle
regulation of nucleic acid-templated transcription

Function(s)

DNA binding
damaged DNA binding
transcription coactivator activity
RNA binding
DNA-(apurinic or apyrimidinic site) lyase activity
nuclease activity
endonuclease activity
endoribonuclease activity
exonuclease activity
double-stranded DNA 3'-5' exodeoxyribonuclease activity
3'-5' exonuclease activity
oxidoreductase activity
hydrolase activity
lyase activity
site-specific endodeoxyribonuclease activity, specific for altered base
chromatin DNA binding
protein complex binding
phosphoric ester hydrolase activity
T/G mismatch-specific endonuclease activity
poly(A) RNA binding
retroviral 3' processing activity
metal ion binding
NF-kappaB binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1400004481.mm.1	NM_009687.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1400004481.mm.1	NM_009687.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1400004481.mm.1	TC1400000573.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1400004478.mm.1	NM_009687.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1400004478.mm.1	NM_009687.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1400004478.mm.1	TC1400000573.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	528718	-	-