Mm01321080_g1

• Gene Symbol: Parp1
• Gene Name: poly (ADP-ribose) polymerase family, member 1
• Gene Aliases: 5830444G22Rik, AI893648, ARTD1, Adprp, Adprt1, C80510, PARP, PPOL, parp-1, sPARP-1
• Chromosome Location: Chr.1: 180568975 - 180601254 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Parp1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_007415.2	NP_031441.2	10 - 11	1601		89
GenBank mRNA	AK028042.1	-	10 - 11	1620		89
	AK030889.1	-	10 - 11	1604		89
	AK088679.1	-	10 - 11	1605		89
	AK146677.1	-	10 - 11	1622		89
	AK152360.1	-	10 - 11	1622		89
	AK165158.1	-	10 - 11	1621		89
	AK166104.1	-	10 - 11	1653		89
	AK167699.1	-	10 - 11	1593		89
	AK169326.1	-	10 - 11	1622		89
	BC012041.1	-	10 - 11	1601	2648390	89
	X14206.1	-	10 - 11			89

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0100001711.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Parp1

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

telomere maintenance
DNA metabolic process
DNA repair
base-excision repair
double-strand break repair
transcription, DNA-templated
regulation of transcription, DNA-templated
protein ADP-ribosylation
cellular response to DNA damage stimulus
mitochondrion organization
transforming growth factor beta receptor signaling pathway
protein autoprocessing
signal transduction involved in regulation of gene expression
mitochondrial DNA metabolic process
cellular response to insulin stimulus
cellular response to oxidative stress
protein modification process
regulation of growth rate
DNA damage response, detection of DNA damage
mitochondrial DNA repair
positive regulation of transcription from RNA polymerase II promoter
behavioral response to cocaine
positive regulation of SMAD protein import into nucleus
protein poly-ADP-ribosylation
cellular response to superoxide
regulation of single strand break repair
positive regulation of transcription regulatory region DNA binding

Function(s)

DNA binding
chromatin binding
NAD+ ADP-ribosyltransferase activity
protein binding
transcription factor binding
zinc ion binding
transferase activity
transferase activity, transferring glycosyl groups
enzyme binding
protein kinase binding
identical protein binding
poly(A) RNA binding
metal ion binding
protein N-terminus binding
NAD binding
R-SMAD binding