Mm01351840_g1

• Gene Symbol: Edn1
• Gene Name: endothelin 1
• Gene Aliases: ET-1, preproET
• Chromosome Location: Chr.13: 42301270 - 42307989 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Edn1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_010104.3	NP_034234.1	3 - 4	1018		87
GenBank mRNA	AB081657.1	-	3 - 4	404		87
	AK040778.1	-	3 - 4	676		87
	AK152647.1	-	3 - 4	669		87
	AK153437.1	-	3 - 4	673		87
	BC029547.1	-	3 - 4	812	5059522	87
	D43775.1	-	3 - 4	729		87
	U35233.1	-	3 - 4	423		87

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1300000481.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Edn1

Panther Classification:

Molecular Function -

peptide hormone

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
skeletal system development
prostaglandin biosynthetic process
patterning of blood vessels
response to hypoxia
in utero embryonic development
histamine secretion
regulation of systemic arterial blood pressure by endothelin
regulation of pH
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
protein kinase C-activating G-protein coupled receptor signaling pathway
cell-cell signaling
heart development
respiratory gaseous exchange
body fluid secretion
regulation of blood pressure
positive regulation of cell proliferation
dorsal/ventral pattern formation
positive regulation of heart rate
positive regulation of cardiac muscle hypertrophy
positive regulation of receptor biosynthetic process
neural crest cell development
phosphatidylinositol 3-kinase signaling
artery smooth muscle contraction
vein smooth muscle contraction
glucose transport
cell growth
regulation of vasoconstriction
sensory perception of pain
calcium-mediated signaling
peptide hormone secretion
nitric oxide transport
positive regulation of cell migration
negative regulation of cAMP biosynthetic process
phospholipase D-activating G-protein coupled receptor signaling pathway
negative regulation of cellular protein metabolic process
positive regulation of prostaglandin secretion
negative regulation of smooth muscle cell apoptotic process
intracellular signal transduction
positive regulation of urine volume
positive regulation of renal sodium excretion
epithelial fluid transport
vasoconstriction
protein kinase C deactivation
middle ear morphogenesis
positive regulation of odontogenesis
superoxide anion generation
rhythmic excitation
positive regulation of MAP kinase activity
positive regulation of JUN kinase activity
positive regulation of cell size
positive regulation of mitotic nuclear division
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle contraction
positive regulation of hormone secretion
negative regulation of hormone secretion
inositol phosphate-mediated signaling
blood vessel morphogenesis
positive regulation of smooth muscle cell proliferation
regulation of blood vessel size
cartilage development
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
negative regulation of nitric-oxide synthase biosynthetic process
membrane depolarization
regulation of sensory perception of pain
positive regulation of sarcomere organization
positive regulation of prostaglandin-endoperoxide synthase activity
positive regulation of neutrophil chemotaxis

Function(s)

receptor binding
cytokine activity
hormone activity
protein binding
endothelin A receptor binding
endothelin B receptor binding