Mm03047841_m1

• Gene Symbol: Rabgef1
• Gene Name: RAB guanine nucleotide exchange factor (GEF) 1
• Gene Aliases: Rab5ef, Rabex5, Rin2
• Chromosome Location: Chr.5: 130171791 - 130214342 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Rabgef1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001199059.1	NP_001185988.1	2 - 3	263		75
	NM_019983.2	NP_064367.1	1 - 2	408		75
GenBank mRNA	AF093590.1	-	2 - 3	239		75
	AK044568.1	-	1 - 2	428		75
	AK146734.1	-	2 - 3	213		75
	BC018229.1	-	1 - 2	408	4507477	75
	BY285547.1	-	2 - 3	264		75

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0500001526.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Rabgef1

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
negative regulation of leukocyte migration
protein targeting to membrane
transport
endocytosis
protein transport
protein ubiquitination
negative regulation of mast cell activation
negative regulation of mast cell degranulation
positive regulation of GTPase activity
negative regulation of Ras protein signal transduction
negative regulation of receptor-mediated endocytosis
negative regulation of inflammatory response
regulation of Fc receptor mediated stimulatory signaling pathway
negative regulation of interleukin-6 secretion
negative regulation of Kit signaling pathway

Function(s)

DNA binding
protein binding
zinc ion binding
Rab guanyl-nucleotide exchange factor activity
Rab GTPase binding
metal ion binding
ubiquitin protein ligase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0500013783.mm.1	TC0500001526.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500013783.mm.1	NM_001199059.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013783.mm.1	NM_001199059.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013786.mm.1	TC0500001526.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500013786.mm.1	NM_019983.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013786.mm.1	NM_019983.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013785.mm.1	TC0500001526.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500013785.mm.1	NM_019983.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013785.mm.1	NM_019983.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013788.mm.1	TC0500001526.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500013788.mm.1	NM_001199059.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013788.mm.1	NM_001199059.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013788.mm.1	NM_019983.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013788.mm.1	NM_019983.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013787.mm.1	TC0500001526.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500013787.mm.1	NM_001199059.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013787.mm.1	NM_001199059.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013787.mm.1	NM_019983.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013787.mm.1	NM_019983.2	Refseq