Mm03047844_m1

• Gene Symbol: Rabgef1
• Gene Name: RAB guanine nucleotide exchange factor (GEF) 1
• Gene Aliases: Rab5ef, Rabex5, Rin2
• Chromosome Location: Chr.5: 130171791 - 130214342 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Rabgef1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001199059.1	NP_001185988.1	6 - 7	800		159
	NM_019983.2	NP_064367.1	5 - 6	945		159
GenBank mRNA	AF093590.1	-	6 - 7	776		159
	AK044568.1	-	5 - 6	965		159
	AK146734.1	-	6 - 7	750		159
	BC018229.1	-	5 - 6	945	4507477	159

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0500001526.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Rabgef1

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
negative regulation of leukocyte migration
protein targeting to membrane
transport
endocytosis
protein transport
protein ubiquitination
negative regulation of mast cell activation
negative regulation of mast cell degranulation
positive regulation of GTPase activity
negative regulation of Ras protein signal transduction
negative regulation of receptor-mediated endocytosis
negative regulation of inflammatory response
regulation of Fc receptor mediated stimulatory signaling pathway
negative regulation of interleukin-6 secretion
negative regulation of Kit signaling pathway

Function(s)

DNA binding
protein binding
zinc ion binding
Rab guanyl-nucleotide exchange factor activity
Rab GTPase binding
metal ion binding
ubiquitin protein ligase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0500013795.mm.1	TC0500001526.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500013795.mm.1	NM_001199059.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013795.mm.1	NM_001199059.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013795.mm.1	NM_019983.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013795.mm.1	NM_019983.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013797.mm.1	TC0500001526.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500013797.mm.1	NM_001199059.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013797.mm.1	NM_001199059.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013797.mm.1	NM_019983.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500013797.mm.1	NM_019983.2	Refseq