Mm03931550_s1

• Gene Symbol: Six3
• Gene Name: sine oculis-related homeobox 3
• Gene Aliases: E130112M24Rik, Six3a, Six3alpha, Six3b, Six3beta
• Chromosome Location: Chr.17: 85620834 - 85626191 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Six3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011381.4	NP_035511.2	2			105
GenBank mRNA	AK021385.1	-	1	149		106

Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Transcript Location	Amplicon Length
GenBankmRNA	CK622937.1	-	1			Chr. 17 - 85624107 - 85624603 [+] on Build GRCm38	105
GenBankmRNA	BY731327.1	-		149		Chr. - - [-] on Build	106
GenBankmRNA	CK627912.1	-	1			Chr. 17 - 85624330 - 85624920 [+] on Build GRCm38	105

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	SIX homeobox 3, opposite strand 1	Six3os1	D17Mgi26, E130112H22Rik, Rncr1, Six3os	-5.9kb	Anti-sense	Chr. 17 - 85601932 - 85618396 on NCBI Build GRCm38
Downstream	sine oculis-related homeobox 2	Six2		37.5kb	Anti-sense	Chr. 17 - 85662735 - 85688254 on NCBI Build GRCm38

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect genomic DNA. Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Detect Genomic DNA, Mus musculus, 1700, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Six3

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

protein import into nucleus, translocation
eye development
epithelial cell maturation
lens development in camera-type eye
optic vesicle morphogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein import into nucleus
multicellular organism development
brain development
proximal/distal axis specification
neuroblast differentiation
diencephalon development
telencephalon development
forebrain anterior/posterior pattern specification
forebrain dorsal/ventral pattern formation
cell proliferation in forebrain
telencephalon regionalization
pituitary gland development
negative regulation of Wnt signaling pathway
regulation of cell proliferation
camera-type eye development
negative regulation of neuron differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
circadian behavior
lens induction in camera-type eye
regulation of neural retina development
lens fiber cell differentiation
neuroblast migration
regulation of cell cycle phase transition
regulation of neuroblast proliferation
apoptotic process involved in development
lens fiber cell apoptotic process
regulation of neural precursor cell proliferation

Function(s)

RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcription corepressor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
receptor binding
protein binding
histone deacetylase binding
sequence-specific DNA binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1700011768.mm.1	NM_011381.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700011768.mm.1	NM_011381.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1700011768.mm.1	TC1700001279.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1700011769.mm.1	NM_011381.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700011769.mm.1	NM_011381.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1700011769.mm.1	TC1700001279.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1700011771.mm.1	NM_011381.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700011771.mm.1	NM_011381.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1700011771.mm.1	TC1700001279.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1700011772.mm.1	NM_011381.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700011772.mm.1	NM_011381.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1700011772.mm.1	TC1700001279.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1700011770.mm.1	NM_011381.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700011770.mm.1	NM_011381.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1700011770.mm.1	TC1700001279.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	734492	-	-