Mm04207257_g1

• Gene Symbol: Sphk1
• Gene Name: sphingosine kinase 1
• Gene Aliases: 1110006G24Rik, Sk1, Spk1
• Chromosome Location: Chr.11: 116529817 - 116536675 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Sphk1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001172472.1	NP_001165943.1	3 - 4	603		102
	NM_001172473.1	NP_001165944.1	3 - 4	489		102
	NM_001172475.1	NP_001165946.1	3 - 4	528		102
	NM_011451.3	NP_035581.1	1 - 2	260		102
	NM_025367.6	NP_079643.2	3 - 4	486		102
GenBank mRNA	AF068748.1	-	3 - 4	528		102
	AF068749.1	-	1 - 2	260		102
	AF415213.1	-	1 - 2	158		102
	AK028667.1	-	1 - 2	2550		102
	AK136289.1	-	2 - 3	274		102
	AK155332.1	-	3 - 4	588		102
	AK160900.1	-	3 - 4	479		102
	BC037710.1	-	3 - 4	401	4221357	102

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100001935.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Apoptosis, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Sphk1

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

blood vessel development
positive regulation of protein phosphorylation
positive regulation of neurotransmitter secretion
sphingosine-1-phosphate signaling pathway
sphingosine metabolic process
inflammatory response
brain development
positive regulation of cell proliferation
positive regulation of peptidyl-threonine phosphorylation
regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of neuron projection development
phosphorylation
cyclooxygenase pathway
calcium-mediated signaling
positive regulation of cell growth
positive regulation of cell migration
positive regulation of protein ubiquitination
regulation of interleukin-1 beta production
positive regulation of NF-kappaB import into nucleus
negative regulation of apoptotic process
positive regulation of angiogenesis
positive regulation of mitotic cell cycle
positive regulation of smooth muscle contraction
sphingosine biosynthetic process
lipid phosphorylation
positive regulation of fibroblast proliferation
positive regulation of NF-kappaB transcription factor activity

Function(s)

nucleotide binding
magnesium ion binding
DNA binding
calmodulin binding
ATP binding
sphinganine kinase activity
kinase activity
transferase activity
D-erythro-sphingosine kinase activity
sphingosine-1-phosphate receptor activity
protein phosphatase 2A binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100018378.mm.1	NM_011451.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100018378.mm.1	NM_011451.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1100018378.mm.1	TC1100001935.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1100018382.mm.1	NM_001172472.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100018382.mm.1	NM_001172472.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100018382.mm.1	NM_001172473.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100018382.mm.1	NM_001172473.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100018382.mm.1	NM_001172475.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100018382.mm.1	NM_001172475.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100018382.mm.1	NM_011451.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100018382.mm.1	NM_011451.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1100018382.mm.1	NM_025367.6.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100018382.mm.1	NM_025367.6	Refseq
Affymetrix Mouse Clariom S Array	PSR1100018382.mm.1	TC1100001935.mm.1	MTA TC