Mm04410156_m1

• Gene Symbol: Runx2
• Gene Name: runt related transcription factor 2
• Gene Aliases: AML3, Cbf, Cbfa-1, Cbfa1, LS3, Osf2, PEBP2aA, Pebp2a1, Pebpa2a
• Chromosome Location: Chr.17: 44495986 - 44814831 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Runx2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NR_073392.1		2 - 3	427		81
GenBank mRNA	AF053954.1	-	2 - 3	257		81
	AF053955.1	-	1 - 2	91		81
	DQ458792.1	-	2 - 3	428		81

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	suppressor of Ty 3	Supt3	2310066G22Rik, AI315192, SPT3, SPT3L, Supt3h		Anti-sense	Chr. 17 - 44777171 - 45119294 on NCBI Build GRCm38
Downstream	RIKEN cDNA 4930564C03 gene	4930564C03Rik		65.4kb	Sense	Chr. 17 - 44879704 - 44880885 on NCBI Build GRCm38

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1700002138.mm.1

• Set Membership: Amplicon length between 71 and 85, Mus musculus, 1700, Probe spans exons

Panther Classification:

Molecular Function -

Runt transcription factor

Gene Ontology Categories:

Process(es)

skeletal system development
osteoblast differentiation
endochondral ossification
osteoblast fate commitment
chondrocyte differentiation
chondrocyte development
osteoblast development
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
positive regulation of gene expression
hemopoiesis
neuron differentiation
T cell differentiation
regulation of ossification
BMP signaling pathway
positive regulation of chondrocyte differentiation
embryonic forelimb morphogenesis
regulation of fibroblast growth factor receptor signaling pathway
odontogenesis of dentin-containing tooth
regulation of odontogenesis of dentin-containing tooth
regulation of osteoblast differentiation
positive regulation of osteoblast differentiation
positive regulation of ossification
negative regulation of smoothened signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell maturation
embryonic cranial skeleton morphogenesis
skeletal system morphogenesis
stem cell differentiation
cellular response to BMP stimulus
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
ATP binding
transcription factor binding
protein domain specific binding
histone deacetylase binding
bHLH transcription factor binding
transcription regulatory region DNA binding
repressing transcription factor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1700020022.mm.1	NM_001146038.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020022.mm.1	NM_001271627.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020022.mm.1	NM_009820.5	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020022.mm.1	NR_073392.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020022.mm.1	TC1700002138.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1700020009.mm.1	NM_001145920.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020009.mm.1	NM_001146038.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020009.mm.1	NM_001271627.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020009.mm.1	NM_001271630.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020009.mm.1	NM_001271631.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020009.mm.1	NM_009820.5	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020009.mm.1	NR_073392.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020009.mm.1	NR_073425.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020009.mm.1	TC1700002138.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1700020019.mm.1	NM_001146038.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020019.mm.1	NM_001271627.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020019.mm.1	NM_009820.5	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020019.mm.1	NR_073392.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020019.mm.1	TC1700002138.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1700020027.mm.1	NR_073392.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020027.mm.1	TC1700002138.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1700020020.mm.1	NM_001146038.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020020.mm.1	NM_001271627.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020020.mm.1	NM_009820.5	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020020.mm.1	NR_073392.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020020.mm.1	TC1700002138.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1700020025.mm.1	NM_001146038.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020025.mm.1	NM_001271627.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020025.mm.1	NM_009820.5	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020025.mm.1	NR_073392.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020025.mm.1	TC1700002138.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1700020026.mm.1	NM_001146038.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020026.mm.1	NM_001271627.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020026.mm.1	NM_009820.5	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020026.mm.1	NR_073392.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700020026.mm.1	TC1700002138.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	507825	-	-