Mm04410995_m1

• Gene Symbol: Esr2
• Gene Name: estrogen receptor 2 (beta)
• Gene Aliases: ER[b], ERbeta, Estrb
• Chromosome Location: Chr.12: 76120419 - 76177259 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Esr2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NR_104386.1		5 - 6	1357		92
GenBank mRNA	AK054301.1	-	5 - 6	1358		92

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	spectrin repeat containing, nuclear envelope 2	Syne2	6820443O06Rik, AW546258, D12Ertd777e, NUA, Nesp2g, mKIAA1011	-22.9kb	Anti-sense	Chr. 12 - 75818318 - 76110928 on NCBI Build GRCm38
Downstream	testis expressed gene 21	Tex21	4931406F04Rik, 4931412D23Rik, 4931421K24Rik, tsec-2	53.1kb	Sense	Chr. 12 - 76198687 - 76246758 on NCBI Build GRCm38

More Information

• Set Membership: Amplicon length between 86 and 100, Mus musculus, Probe spans exons

Gene Ontology Categories:

Process(es)

negative regulation of transcription by RNA polymerase II
ovarian follicle development
behavioral fear response
neuron migration
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription by RNA polymerase II
brain development
learning or memory
negative regulation of cell population proliferation
hormone-mediated apoptotic signaling pathway
intracellular steroid hormone receptor signaling pathway
intracellular estrogen receptor signaling pathway
response to testosterone
regulation of cell population proliferation
positive regulation of apoptotic process
steroid hormone mediated signaling pathway
regulation of neuron apoptotic process
estrous cycle
positive regulation of epidermal growth factor receptor signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription by RNA polymerase II
negative regulation of behavior
negative regulation of smooth muscle cell proliferation
negative regulation of epithelial cell proliferation
positive regulation of DNA-binding transcription factor activity
Sertoli cell proliferation
uterus development
vagina development
negative regulation of cell death
prostate gland epithelium morphogenesis
epithelial cell maturation involved in prostate gland development
negative regulation of androgen receptor signaling pathway
positive regulation of ERK1 and ERK2 cascade
negative regulation of neuron death
negative regulation of feeding behavior
negative regulation of reactive oxygen species metabolic process

Function(s)

RNA polymerase II cis-regulatory region sequence-specific DNA binding
core promoter sequence-specific DNA binding
DNA binding
DNA-binding transcription factor activity
steroid hormone receptor activity
nuclear receptor activity
steroid binding
protein binding
zinc ion binding
lipid binding
enzyme binding
estrogen receptor activity
estrogen response element binding
hormone binding
peroxisome proliferator activated receptor binding
sequence-specific DNA binding
metal ion binding
estradiol binding
steroid hormone binding