Mm07293269_g1

• Gene Symbol: Ins2
• Gene Name: insulin II
• Gene Aliases: AA986540, Ins-2, InsII, Mody, Mody4, proinsulin
• Chromosome Location: Chr.7: 142678656 - 142679708 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Ins2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001185083.1	NP_001172012.1	1 - 2	48		74
GenBank mRNA	GQ915612.1	-	1 - 2	48		74

More Information

Additional Information:

This assay is in the 5'UTR region of the GQ915612.1, NM_001185083.1 transcripts.

• Set Membership: Amplicon length between 71 and 85, Detect Genomic DNA, Mus musculus, Probe spans exons

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
activation of MAPK activity
negative regulation of acute inflammatory response
carbohydrate metabolic process
glucose metabolic process
regulation of cellular amino acid metabolic process
acute-phase response
ER overload response
G-protein coupled receptor signaling pathway
activation of JUN kinase activity
myoblast fusion
positive regulation of cell proliferation
insulin receptor signaling pathway
regulation of gene expression
positive regulation of phosphatidylinositol 3-kinase signaling
myotube differentiation
glucose transport
lipid catabolic process
regulation of transmembrane transporter activity
activation of protein kinase B activity
positive regulation of cellular protein metabolic process
negative regulation of protein oligomerization
regulation of protein localization
negative regulation of NAD(P)H oxidase activity
wound healing
negative regulation of protein catabolic process
regulation of phosphorylation
glucose homeostasis
regulation of protein binding
positive regulation of MAPK cascade
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of glycogen biosynthetic process
positive regulation of DNA replication
negative regulation of glycogen catabolic process
positive regulation of glycolytic process
positive regulation of mitotic nuclear division
negative regulation of proteolysis
negative regulation of fatty acid metabolic process
positive regulation of glucose import
positive regulation of insulin receptor signaling pathway
alpha-beta T cell activation
regulation of protein secretion
negative regulation of protein secretion
positive regulation of cytokine secretion
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of lipid catabolic process
positive regulation of NF-kappaB transcription factor activity
positive regulation of protein kinase B signaling
fatty acid homeostasis
canonical Wnt signaling pathway
negative regulation of respiratory burst involved in inflammatory response
positive regulation of respiratory burst
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
positive regulation of protein localization to nucleus
negative regulation of feeding behavior

Function(s)

protease binding
insulin receptor binding
insulin-like growth factor receptor binding
hormone activity
protein complex binding
identical protein binding