Rn00451964_m1

• Gene Symbol: Scn5a
• Gene Name: sodium channel, voltage-gated, type V, alpha subunit
• Gene Aliases: Nav1.5, SCAL
• Chromosome Location: Chr.8: 128169191 - 128266639 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Scn5a
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001160162.1	NP_001153634.1	5 - 6	814		70
	NM_013125.2	NP_037257.1	5 - 6	814		70
	XM_006244076.2	XP_006244138.1	5 - 6	984		70
	XM_008766670.1	XP_008764892.1	5 - 6	2012		70
	XM_008766671.1	XP_008764893.1	5 - 6	2012		70
GenBank mRNA	AF353637.1	-	4 - 5	617		70
	M27902.1	-	5 - 6	814		70

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0800003548.rn.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Scn5a

Gene Ontology Categories:

Process(es)

regulation of heart rate
cardiac ventricle development
brainstem development
sodium ion transport
positive regulation of heart rate
positive regulation of sodium ion transport
response to organic cyclic compound
response to denervation involved in regulation of muscle adaptation
neuronal action potential
telencephalon development
cerebellum development
regulation of ion transmembrane transport
sodium ion transmembrane transport
odontogenesis of dentin-containing tooth
positive regulation of action potential
positive regulation of epithelial cell proliferation
membrane depolarization
cardiac muscle contraction
regulation of ventricular cardiac muscle cell membrane repolarization
regulation of atrial cardiac muscle cell membrane depolarization
regulation of atrial cardiac muscle cell membrane repolarization
regulation of ventricular cardiac muscle cell membrane depolarization
cellular response to calcium ion
cardiac muscle cell action potential involved in contraction
regulation of cardiac muscle cell contraction
ventricular cardiac muscle cell action potential
membrane depolarization during action potential
membrane depolarization during cardiac muscle cell action potential
SA node cell action potential
membrane depolarization during AV node cell action potential
membrane depolarization during SA node cell action potential
membrane depolarization during Purkinje myocyte cell action potential
membrane depolarization during bundle of His cell action potential
AV node cell to bundle of His cell communication
bundle of His cell to Purkinje myocyte communication
SA node cell to atrial cardiac muscle cell communication
regulation of heart rate by cardiac conduction
regulation of sodium ion transmembrane transport

Function(s)

voltage-gated sodium channel activity
protein binding
calmodulin binding
fibroblast growth factor binding
enzyme binding
protein kinase binding
ankyrin binding
ubiquitin protein ligase binding
transmembrane transporter binding
nitric-oxide synthase binding
voltage-gated sodium channel activity involved in cardiac muscle cell action potential
voltage-gated sodium channel activity involved in AV node cell action potential
voltage-gated sodium channel activity involved in bundle of His cell action potential
voltage-gated sodium channel activity involved in Purkinje myocyte action potential
voltage-gated sodium channel activity involved in SA node cell action potential
scaffold protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0800028881.rn.1	TC0800003548.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0800028883.rn.1	TC0800003548.rn.1	RTA TC