Assay Details
Gene Symbol: Il6 | ||||||
---|---|---|---|---|---|---|
Interrogated Sequence | Translated Protein | Exon Boundary | Assay Location | IMAGE Clone ID | Amplicon Length | |
RefSeq | NM_012589.2 | NP_036721.1 | 2 - 3 | 270 | 128 | |
GenBank mRNA | M26744.1 | - | 2 - 3 | 270 | 128 |

More Information
Set Membership: |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Matching Ambion siRNAs:
Gene Ontology Categories:

Citations (37)
Selective portal vein embolization and ligation trigger different regenerative responses in the rat liver.
- Authors
- Furrer K, Tian Y, Pfammatter T, Jochum W, El-Badry AM, Graf R, Clavien PA
- Journal
- Hepatology - Page No 1615 (Thu May 01 00:00:00 EDT 2008)
- Volume (Year)
- 47 (2008)
- Product Usage
- -
Obesity alters cytokine gene expression and promotes liver injury in rats with acute pancreatitis.
- Authors
- Segersvard R, Tsai JA, Herrington MK, Wang F
- Journal
- Obesity (Silver Spring) - Page No 23 (Tue Jan 01 00:00:00 EST 2008)
- Volume (Year)
- 16 (2008)
- Product Usage
- -
Lineage-negative bone marrow cells protect against chronic renal failure.
- Authors
- Alexandre CS, Volpini RA, Shimizu MH, Sanches TR, Semedo P, di Jura VL, Camara NO, Seguro AC, Andrade L
- Journal
- Stem Cells - Page No 682 (Sun Mar 01 00:00:00 EST 2009)
- Volume (Year)
- 27 (2009)
- Product Usage
- -
JAK/STAT3 pathway is activated in spinal cord microglia after peripheral nerve injury and contributes to neuropathic pain development in rat.
- Authors
- Dominguez E, Rivat C, Pommier B, Mauborgne A, Pohl M
- Journal
- J Neurochem - Page No 50 (Wed Oct 01 00:00:00 EDT 2008)
- Volume (Year)
- 107 (2008)
- Product Usage
- -
Does estrogen contribute to the hepatic regeneration following portal branch ligation in rats?
- Authors
- Kawai T, Yokoyama Y, Kawai S, Yokoyama S, Oda K, Nagasaka T, Nagino M, Chaudry IH, Nimura Y
- Journal
- Am J Physiol Gastrointest Liver Physiol - Page No G582 (Thu Feb 01 00:00:00 EST 2007)
- Volume (Year)
- 292 (2007)
- Product Usage
- -
Inchinkoto, an herbal medicine, exerts beneficial effects in the rat liver under stress with hepatic ischemia-reperfusion and subsequent hepatectomy.
- Authors
- Kawai K, Yokoyama Y, Kokuryo T, Watanabe K, Kitagawa T, Nagino M
- Journal
- Ann Surg - Page No 692 (Thu Apr 01 00:00:00 EDT 2010)
- Volume (Year)
- 251 (2010)
- Product Usage
- -
Effects of estradiol on regulation of corticotropin-releasing factor gene and interleukin-6 production via estrogen receptor type beta in hypothalamic 4B cells.
- Authors
- Ogura E, Kageyama K, Hanada K, Kasckow J, Suda T
- Journal
- Peptides - Page No 456 (Sat Mar 01 00:00:00 EST 2008)
- Volume (Year)
- 29 (2008)
- Product Usage
- -
Estrogen promotes hepatic regeneration via activating serotonin signal.
- Authors
- Kitagawa T, Yokoyama Y, Kokuryo T, Kawai T, Watanabe K, Kawai K, Nagino M
- Journal
- Shock - Page No 615 (Mon Jun 01 00:00:00 EDT 2009)
- Volume (Year)
- 31 (2009)
- Product Usage
- -
Retinoic acid therapy attenuates the severity of tuberculosis while altering lymphocyte and macrophage numbers and cytokine expression in rats infected with Mycobacterium tuberculosis.
- Authors
- Yamada H, Mizuno S, Ross AC, Sugawara I
- Journal
- J Nutr - Page No 2696 (Sat Dec 01 00:00:00 EST 2007)
- Volume (Year)
- 137 (2007)
- Product Usage
- -
Cytokines are produced locally by myocytes in rat skeletal muscle during endotoxemia.
- Authors
- Borge BA, Kalland KH, Olsen S, Bletsa A, Berggreen E, Wiig H
- Journal
- Am J Physiol Heart Circ Physiol - Page No H735 (Sun Mar 01 00:00:00 EST 2009)
- Volume (Year)
- 296 (2009)
- Product Usage
- -
The peptide NDP-MSH induces phenotype changes in the heart that resemble ischemic preconditioning.
- Authors
- Catania A, Lonati C, Sordi A, Leonardi P, Carlin A, Gatti S
- Journal
- Peptides - Page No 116 (Fri Jan 01 00:00:00 EST 2010)
- Volume (Year)
- 31 (2010)
- Product Usage
- -
Influence of endothelin 1 receptor inhibition on functional, structural and molecular changes in the rat heart after irradiation.
- Authors
- Boerma M, Wang J, Kulkarni A, Roberto KA, Qiu X, Kennedy RH, Hauer-Jensen M
- Journal
- Radiat Res - Page No 275 (Mon Sep 01 00:00:00 EDT 2008)
- Volume (Year)
- 170 (2008)
- Product Usage
- -
Transcriptional regulation of scar gene expression in primary astrocytes.
- Authors
- Gris P, Tighe A, Levin D, Sharma R, Brown A
- Journal
- Glia - Page No 1145 (Wed Aug 15 00:00:00 EDT 2007)
- Volume (Year)
- 55 (2007)
- Product Usage
- -
Synergistic effects of cAMP-dependent signalling pathways and IL-1 on IL-6 production by H19-7/IGF-IR neuronal cells.
- Authors
- Bergamaschi A, Corsi M, Garnier MJ
- Journal
- Cell Signal - Page No 1679 (Sun Oct 01 00:00:00 EDT 2006)
- Volume (Year)
- 18 (2006)
- Product Usage
- -
Rutin supplementation in the diet has protective effects against toxicant-induced hippocampal injury by suppression of microglial activation and pro-inflammatory cytokines: protective effect of rutin against toxicant-induced hippocampal injury.
- Authors
- Koda T, Kuroda Y, Imai H
- Journal
- Cell Mol Neurobiol - Page No 523 (Mon Jun 01 00:00:00 EDT 2009)
- Volume (Year)
- 29 (2009)
- Product Usage
- -
SOCS3-mediated blockade of JAK/STAT3 signaling pathway reveals its major contribution to spinal cord neuroinflammation and mechanical allodynia after peripheral nerve injury.
- Authors
- Dominguez E, Mauborgne A, Mallet J, Desclaux M, Pohl M
- Journal
- J Neurosci - Page No 5754 (Wed Apr 21 00:00:00 EDT 2010)
- Volume (Year)
- 30 (2010)
- Product Usage
- -
Glutamate signaling in chondrocytes and the potential involvement of NMDA receptors in cell proliferation and inflammatory gene expression.
- Authors
- Piepoli T, Mennuni L, Zerbi S, Lanza M, Rovati LC, Caselli G
- Journal
- Osteoarthritis Cartilage - Page No 1076 (Sat Aug 01 00:00:00 EDT 2009)
- Volume (Year)
- 17 (2009)
- Product Usage
- -
Differential implication of proinflammatory cytokine interleukin-6 in the development of cephalic versus extracephalic neuropathic pain in rats.
- Authors
- Latremoliere A, Mauborgne A, Masson J, Bourgoin S, Kayser V, Hamon M, Pohl M
- Journal
- J Neurosci - Page No 8489 (Wed Aug 20 00:00:00 EDT 2008)
- Volume (Year)
- 28 (2008)
- Product Usage
- -
Effects of endotoxaemia on protein metabolism in rat fast-twitch skeletal muscle and myocardium.
- Authors
- Murton AJ, Alamdari N, Gardiner SM, Constantin-Teodosiu D, Layfield R, Bennett T, Greenhaff PL
- Journal
- Plos One - Page No e6945 (Thu Jan 01 00:00:00 EST 2009)
- Volume (Year)
- 4 (2009)
- Product Usage
- -
Effects of a new bioactive lipid-based drug carrier on cultured hepatic stellate cells and liver fibrosis in bile duct-ligated rats.
- Authors
- Adrian JE, Poelstra K, Scherphof GL, Meijer DK, van Loenen-Weemaes AM, Reker-Smit C, Morselt HW, Zwiers P, Kamps JA
- Journal
- J Pharmacol Exp Ther - Page No 536 (Tue May 01 00:00:00 EDT 2007)
- Volume (Year)
- 321 (2007)
- Product Usage
- -
Is there any effect of renal failure on the hepatic regeneration capacity following partial hepatectomy in rats?
- Authors
- Kawai T, Yokoyama Y, Nagino M, Kitagawa T, Nimura Y
- Journal
- Biochem Biophys Res Commun - Page No 311 (Fri Jan 12 00:00:00 EST 2007)
- Volume (Year)
- 352 (2007)
- Product Usage
- -
Perioperative infliximab application ameliorates acute rejection associated inflammation after intestinal transplantation.
- Authors
- Pech T, Finger T, Fujishiro J, Praktiknjo M, Ohsawa I, Abu-Elmagd K, Limmer A, Hirner A, Kalff JC, Schaefer N
- Journal
- Am J Transplant - Page No 2431 (Mon Nov 01 00:00:00 EDT 2010)
- Volume (Year)
- 10 (2010)
- Product Usage
- -
Noradrenaline acting at beta-adrenoceptors induces expression of IL-1beta and its negative regulators IL-1ra and IL-1RII, and drives an overall anti-inflammatory phenotype in rat cortex.
- Authors
- McNamee EN, Griffin EW, Ryan KM, Ryan KJ, Heffernan S, Harkin A, Connor TJ
- Journal
- Neuropharmacology - Page No 37 (Thu Jul 01 00:00:00 EDT 2010)
- Volume (Year)
- 59 (2010)
- Product Usage
- -
Dietary supplementation of tetradecylthioacetic acid increases feed intake but reduces body weight gain and adipose depot sizes in rats fed on high-fat diets.
- Authors
- Wensaas AJ, Rustan AC, Rokling-Andersen MH, Caesar R, Jensen J, Kaalhus O, Graff BA, Gudbrandsen OA, Berge RK, Drevon CA
- Journal
- Diabetes Obes Metab - Page No 1034 (Sun Nov 01 00:00:00 EDT 2009)
- Volume (Year)
- 11 (2009)
- Product Usage
- -
AAV2/1-TNFR:Fc gene delivery prevents periodontal disease progression.
- Authors
- Cirelli JA, Park CH, MacKool K, Taba M Jr, Lustig KH, Burstein H, Giannobile WV
- Journal
- Gene Ther - Page No 426 (Sun Mar 01 00:00:00 EST 2009)
- Volume (Year)
- 16 (2009)
- Product Usage
- -
Mechanisms involved in ultrafine carbon black-induced release of IL-6 from primary rat epithelial lung cells.
- Authors
- Totlandsdal AI, Refsnes M, Lag M
- Journal
- Toxicol In Vitro - Page No 10 (Mon Feb 01 00:00:00 EST 2010)
- Volume (Year)
- 24 (2010)
- Product Usage
- -
15-deoxy-delta 12,14-prostaglandin J2 prevents inflammatory response and endothelial cell damage in rats with acute obstructive cholangitis.
- Authors
- Watanabe K, Yokoyama Y, Kokuryo T, Kawai K, Kitagawa T, Seki T, Nakagawa A, Nagino M
- Journal
- Am J Physiol Gastrointest Liver Physiol - Page No G410 (Mon Mar 01 00:00:00 EST 2010)
- Volume (Year)
- 298 (2010)
- Product Usage
- -
Pro-inflammatory potential of ultrafine particles in mono- and co-cultures of primary cardiac cells.
- Authors
- Totlandsdal AI, Skomedal T, Lag M, Osnes JB, Refsnes M
- Journal
- Toxicology - Page No 23 (Fri May 02 00:00:00 EDT 2008)
- Volume (Year)
- 247 (2008)
- Product Usage
- -
The role of proliferator-activated receptor gamma coactivator-1alpha in the fatty-acid-dependent transcriptional control of interleukin-10 in hepatic cells of rodents.
- Authors
- Morari J, Torsoni AS, Anhe GF, Roman EA, Cintra DE, Ward LS, Bordin S, Velloso LA
- Journal
- Metabolism - Page No 215 (Mon Feb 01 00:00:00 EST 2010)
- Volume (Year)
- 59 (2010)
- Product Usage
- -
Segmental cholangitis impairs hepatic regeneration capacity after partial hepatectomy in rats.
- Authors
- Watanabe K, Yokoyama Y, Kokuryo T, Kawai K, Kitagawa T, Seki T, Nakagawa A, Nagino M
- Journal
- Hpb (Oxford) - Page No 664 (Wed Dec 01 00:00:00 EST 2010)
- Volume (Year)
- 12 (2010)
- Product Usage
- -
Influence of immunosuppression on alloresponse, inflammation and contractile function of graft after intestinal transplantation.
- Authors
- Fujishiro J, Pech TC, Finger TF, Praktinjo M, Stoffels B, Standop J, Abu-Elmagd K, Tuerler A, Hirner A, Kalff JC, Schaefer N
- Journal
- Am J Transplant - Page No 1545 (Thu Jul 01 00:00:00 EDT 2010)
- Volume (Year)
- 10 (2010)
- Product Usage
- -
Molecular determinants of the profibrogenic effects of endothelin-1 in pancreatic stellate cells.
- Authors
- Jonitz A, Fitzner B, Jaster R
- Journal
- World J Gastroenterol - Page No 4143 (Mon Sep 07 00:00:00 EDT 2009)
- Volume (Year)
- 15 (2009)
- Product Usage
- -
Influence of mast cells on outcome after heterotopic cardiac transplantation in rats.
- Authors
- Boerma M, Fiser WP, Hoyt G, Berry GJ, Joseph L, Joseph J, Wang J, Crew MD, Robbins RC, Hauer-Jensen M
- Journal
- Transpl Int - Page No 256 (Thu Mar 01 00:00:00 EST 2007)
- Volume (Year)
- 20 (2007)
- Product Usage
- -
Deleterious effects of dihydrotestosterone on cerebral ischemic injury.
- Authors
- Cheng J, Alkayed NJ, Hurn PD
- Journal
- J Cereb Blood Flow Metab - Page No 1553 (Sat Sep 01 00:00:00 EDT 2007)
- Volume (Year)
- 27 (2007)
- Product Usage
- -
Noradrenaline acting at central beta-adrenoceptors induces interleukin-10 and suppressor of cytokine signaling-3 expression in rat brain: implications for neurodegeneration.
- Authors
- McNamee EN, Ryan KM, Griffin EW, Gonzalez-Reyes RE, Ryan KJ, Harkin A, Connor TJ
- Journal
- Brain Behav Immun - Page No 660 (Sat May 01 00:00:00 EDT 2010)
- Volume (Year)
- 24 (2010)
- Product Usage
- -
Dexamethasone reverses monocrotaline-induced pulmonary arterial hypertension in rats.
- Authors
- Price LC, Montani D, Tcherakian C, Dorfmuller P, Souza R, Gambaryan N, Chaumais MC, Shao DM, Simonneau G, Howard LS, Adcock IM, Wort SJ, Humbert M, Perros F
- Journal
- Eur Respir J - Page No (Fri Aug 06 00:00:00 EDT 2010)
- Volume (Year)
- (2010)
- Product Usage
- -
Calcium/calcineurin signaling in primary cortical astrocyte cultures: Rcan1-4 and cyclooxygenase-2 as NFAT target genes.
- Authors
- Canellada A, Ramirez BG, Minami T, Redondo JM, Cano E
- Journal
- Glia - Page No 709 (Thu May 01 00:00:00 EDT 2008)
- Volume (Year)
- 56 (2008)
- Product Usage
- -
