Rn00565062_m1 Best Coverage

• Gene Symbol: Cd74
• Gene Name: Cd74 molecule, major histocompatibility complex, class II invariant chain
• Gene Aliases: INVG34
• Chromosome Location: Chr.18: 56071420 - 56080851 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Cd74
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_013069.2	NP_037201.1	1 - 2	172		68
	XM_006254761.2	XP_006254823.1	1 - 2	230		68
GenBank mRNA	BC059152.1	-	1 - 2	153	6890709	68
	CB696567.1	-	1 - 2	182		68
	FQ219430.1	-	1 - 2	155		68
	FQ225098.1	-	1 - 2	147		68
	FQ227357.1	-	1 - 2	149		68
	FQ227455.1	-	1 - 2	152		68
	FQ227561.1	-	1 - 2	154		68
	FQ228116.1	-	1 - 2	155		68
	FQ231756.1	-	1 - 2	156		68
	FQ232412.1	-	1 - 2	197		68
	FQ232423.1	-	1 - 2	186		68
	FQ232867.1	-	1 - 2	156		68
	FQ232996.1	-	1 - 2	149		68
	FQ233568.1	-	1 - 2	155		68
	FQ233706.1	-	1 - 2	155		68
	FQ234457.1	-	1 - 2	158		68
	X13044.1	-	1 - 2	128		68
	X14254.1	-	1 - 2	136		68

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC1800000616.rn.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Recommended Assay, Rattus norvegicus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Cd74

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

activation of MAPK activity
prostaglandin biosynthetic process
positive regulation of cytokine-mediated signaling pathway
positive regulation of dendritic cell antigen processing and presentation
negative regulation of peptide secretion
positive regulation of type 2 immune response
negative regulation of mature B cell apoptotic process
protein complex assembly
intracellular protein transport
defense response
signal transduction
cell proliferation
immunoglobulin mediated immune response
cytokine-mediated signaling pathway
antigen processing and presentation
antigen processing and presentation of exogenous peptide antigen via MHC class II
positive regulation of B cell proliferation
macrophage migration inhibitory factor signaling pathway
negative regulation of apoptotic process
negative regulation of DNA damage response, signal transduction by p53 class mediator
positive thymic T cell selection
negative thymic T cell selection
negative regulation of T cell differentiation
positive regulation of T cell differentiation
positive regulation of fibroblast proliferation
positive regulation of peptidyl-tyrosine phosphorylation
chaperone mediated protein folding requiring cofactor
positive regulation of macrophage cytokine production
positive regulation of ERK1 and ERK2 cascade
positive regulation of neutrophil chemotaxis
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of chemokine (C-X-C motif) ligand 2 production

Function(s)

beta-amyloid binding
cytokine receptor activity
cytokine binding
MHC class II protein complex binding
macrophage migration inhibitory factor binding
MHC class II protein binding
MHC class II protein binding, via antigen binding groove
protein binding involved in protein folding
nitric-oxide synthase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Agilent Whole Rat Genome Microarray 4x44K v2	A_44_P549494	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	216619	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	929190	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	799751	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	796592	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	774402	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	343853	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	718430	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	50700	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	96642	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_44_P549494	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_44_P549494	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_44_P549494	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_44_P549494	-	-
Matsumoto (Agilent Rat cDNA Microarray G4105A)	700542793	-	-
Matsumoto (Agilent Rat cDNA Microarray G4105A)	702147295	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	88541	-	-
Agilent Rat cDNA Microarray (G4105A)	700542793	-	-
Agilent Rat cDNA Microarray (G4105A)	702147295	-	-

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Gene 1.0 ST Array	10802017	-	-
Affymetrix Rat Gene 1.0 ST Array	10802015	-	-
Affymetrix Rat Gene 1.0 ST Array	10802021	-	-
Affymetrix Rat Gene 1.0 ST Array	10802018	-	-
Affymetrix Rat Gene 1.0 ST Array	10802019	-	-
Affymetrix Rat Gene 1.0 ST Array	10802014	-	-
Affymetrix Rat Gene 1.0 ST Array	10802016	-	-
Affymetrix Rat Gene 1.0 ST Array	10802022	-	-
Affymetrix Rat Gene 1.1 ST Array	10802013	-	-
Rat Genome 230 2.0 Array	1367679_PM_at	-	-
Rat Genome 230 2.0 Array	1367679_at	-	-
Affymetrix HT Rat Focus Array	1367679_PM_at	-	-
Affymetrix HT Rat Focus Array	1367679_at	-	-
Affymetrix Rat Clariom S Assay	PSR1800004479.rn.1	TC1800000616.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR1800004481.rn.1	TC1800000616.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR1800004483.rn.1	TC1800000616.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR1800004480.rn.1	TC1800000616.rn.1	RTA TC
Rat Expression Set 230	1367679_PM_at	-	-
Rat Expression Set 230	1367679_at	-	-
Affymetrix Rat Gene 1.0 ST Array	10802013	-	-
Rat Genome U34 Set	X13044_at	-	-
Rat Genome U34 Set	X14254cds_g_at	-	-
Rat Genome U34 Set	X14254cds_at	-	-
Rat Genome U34 Set	X13044_g_at	-	-
Rat Genome U34 Set	rc_AI105172_i_at	-	-
Rat Genome U34 Set	rc_AI105172_r_at	-	-

Array Name	Probe IDs	Targets	Target Type
ABI Rat Genome Survey Microarray	21537743	-	-

Array Name	Probe IDs	Targets	Target Type
Illumina ratRef-12 v1.0 expression beadchip	ILMN_1373953	-	-
RatRef-12 Expression BeadChip	ILMN_66384	-	-