Rn00569203_m1 Best Coverage

• Gene Symbol: Isl1
• Gene Name: ISL LIM homeobox 1
• Gene Aliases: Isl-1, isl-1=homeobox
• Chromosome Location: Chr.2: 48488911 - 48501217 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Isl1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_017339.3	NP_059035.3	3 - 4	485		106
GenBank mRNA	AY557632.1	-	3 - 4	480		106
	S69329.1	-	3 - 4	485		106
	X53258.1	-	3 - 4	588		106

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0200002949.rn.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, 3' Most, Recommended Assay, Rattus norvegicus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Isl1

Gene Ontology Categories:

Process(es)

negative regulation of transcription by RNA polymerase II
neural crest cell migration
heart morphogenesis
secondary heart field specification
outflow tract septum morphogenesis
outflow tract morphogenesis
endocardial cushion morphogenesis
cardiac right ventricle morphogenesis
regulation of secondary heart field cardioblast proliferation
regulation of transcription, DNA-templated
heart development
positive regulation of cell population proliferation
regulation of gene expression
positive regulation of vascular endothelial growth factor production
spinal cord motor neuron cell fate specification
spinal cord motor neuron differentiation
visceral motor neuron differentiation
trigeminal nerve development
pituitary gland development
neuron differentiation
pancreas development
axon regeneration
retinal ganglion cell axon guidance
positive regulation of insulin secretion
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of interferon-gamma production
positive regulation of interleukin-1 alpha production
positive regulation of interleukin-1 beta production
positive regulation of interleukin-12 production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
negative regulation of intracellular estrogen receptor signaling pathway
positive regulation of tyrosine phosphorylation of STAT protein
positive regulation of DNA binding
negative regulation of neuron apoptotic process
negative regulation of neuron differentiation
positive regulation of angiogenesis
positive regulation of transcription by RNA polymerase II
neuron fate commitment
neuron fate specification
mesenchymal cell differentiation
sensory system development
peripheral nervous system neuron development
peripheral nervous system neuron axonogenesis
negative regulation of inflammatory response
ventricular cardiac muscle tissue morphogenesis
pharyngeal system development
cardiac muscle cell myoblast differentiation
innervation
atrial septum morphogenesis
cardiac cell fate determination
cellular response to glucocorticoid stimulus
positive regulation of granulocyte colony-stimulating factor production
negative regulation of protein homodimerization activity
negative regulation of canonical Wnt signaling pathway
positive regulation of macrophage colony-stimulating factor production

Function(s)

RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA binding
chromatin binding
transcription coactivator activity
protein binding
zinc ion binding
nuclear receptor binding
estrogen receptor binding
bHLH transcription factor binding
sequence-specific DNA binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Agilent Whole Rat Genome Microarray 4x44K v2	A_44_P509917	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	655085	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	424820	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	593454	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	715417	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	218413	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	782432	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	622267	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	448884	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	50426	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_44_P509917	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_44_P509917	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_44_P509917	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_44_P509917	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	37529	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	34819	-	-

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Gene 1.0 ST Array	10821487	-	-
Affymetrix Rat Gene 1.0 ST Array	10821490	-	-
Affymetrix Rat Gene 1.0 ST Array	10821489	-	-
Affymetrix Rat Gene 1.0 ST Array	10821488	-	-
Affymetrix Rat Gene 1.0 ST Array	10821492	-	-
Affymetrix Rat Gene 1.0 ST Array	10821491	-	-
Affymetrix Rat Gene 1.1 ST Array	10821486	-	-
Rat Genome 230 2.0 Array	1369681_at	-	-
Rat Genome 230 2.0 Array	1369681_PM_at	-	-
Rat Genome 230 2.0 Array	1396895_at	-	-
Rat Genome 230 2.0 Array	1396895_PM_at	-	-
Affymetrix HT Rat Focus Array	1396895_at	-	-
Affymetrix HT Rat Focus Array	1369681_at	-	-
Affymetrix HT Rat Focus Array	1369681_PM_at	-	-
Affymetrix HT Rat Focus Array	1396895_PM_at	-	-
Affymetrix Rat Clariom S Assay	PSR0200020745.rn.1	TC0200002949.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0200020742.rn.1	TC0200002949.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0200020744.rn.1	TC0200002949.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0200020749.rn.1	TC0200002949.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0200020750.rn.1	TC0200002949.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0200020748.rn.1	TC0200002949.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0200020746.rn.1	TC0200002949.rn.1	RTA TC
Rat Expression Set 230	1369681_at	-	-
Rat Expression Set 230	1369681_PM_at	-	-
Rat Expression Set 230	1396895_PM_at	-	-
Rat Expression Set 230	1396895_at	-	-
Affymetrix Rat Gene 1.0 ST Array	10821486	-	-
Rat Genome U34 Set	S69329_g_at	-	-
Rat Genome U34 Set	S69329_at	-	-
Rat Genome U34 Set	rc_AA944599_at	-	-

Array Name	Probe IDs	Targets	Target Type
ABI Rat Genome Survey Microarray	21414494	-	-

Array Name	Probe IDs	Targets	Target Type
Illumina ratRef-12 v1.0 expression beadchip	ILMN_1371866	-	-
RatRef-12 Expression BeadChip	ILMN_69643	-	-