Rn00575515_m1 Best Coverage

• Gene Symbol: Hand2
• Gene Name: heart and neural crest derivatives expressed 2
• Gene Aliases: -
• Chromosome Location: Chr.16: 36370715 - 36373634 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Hand2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_022696.1	NP_073187.1		587		66
GenBank mRNA	Y08138.1	-		587		66

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect transcript(s) from off target gene(s). Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, 3' Most, Recommended Assay, Rattus norvegicus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Hand2

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

angiogenesis
in utero embryonic development
heart looping
suckling behavior
heart morphogenesis
cardiac right ventricle formation
cardiac neural crest cell migration involved in outflow tract morphogenesis
regulation of secondary heart field cardioblast proliferation
apoptotic process involved in heart morphogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
heart development
adult heart development
mesenchymal cell proliferation
negative regulation of cardiac muscle cell apoptotic process
neural crest cell development
cell differentiation
odontogenesis of dentin-containing tooth
embryonic digit morphogenesis
negative regulation of apoptotic process
negative regulation of DNA binding
negative regulation of sequence-specific DNA binding transcription factor activity
tongue development
negative regulation of osteoblast differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
sympathetic nervous system development
thymus development
peripheral nervous system neuron development
palate development
mesenchyme development
cartilage morphogenesis
coronary artery morphogenesis
visceral serous pericardium development
cardiac neural crest cell development involved in outflow tract morphogenesis
cell proliferation involved in outflow tract morphogenesis
determination of heart left/right asymmetry
cellular response to retinoic acid
cellular response to organic cyclic compound
positive regulation of transcription regulatory region DNA binding
positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process
positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
AT DNA binding
transcription coactivator activity
protein binding
transcription factor binding
activating transcription factor binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
protein dimerization activity
E-box binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Agilent Whole Rat Genome Microarray 4x44K v2	A_64_P130050	-	-
Agilent Whole Rat Genome Microarray 4x44K v2	A_64_P130055	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	669076	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P130050	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P130050	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_64_P130050	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_44_P214837	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_44_P214836	-	-
Agilent Rat cDNA Microarray (G4105A)	701189252	-	-

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Gene 1.0 ST Array	10791505	-	-
Affymetrix Rat Gene 1.0 ST Array	10791506	-	-
Affymetrix Rat Gene 1.1 ST Array	10791504	-	-
Rat Genome 230 2.0 Array	1369817_at	-	-
Rat Genome 230 2.0 Array	1369817_PM_at	-	-
Rat Genome 230 2.0 Array	1374451_at	-	-
Rat Genome 230 2.0 Array	1374451_PM_at	-	-
Affymetrix HT Rat Focus Array	1374451_at	-	-
Affymetrix HT Rat Focus Array	1374451_PM_at	-	-
Affymetrix HT Rat Focus Array	1369817_PM_at	-	-
Affymetrix HT Rat Focus Array	1369817_at	-	-
Affymetrix Rat Clariom S Assay	PSR1600011852.rn.1	TC1600001557.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR1600011851.rn.1	TC1600001557.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR1600011850.rn.1	TC1600001557.rn.1	RTA TC
Rat Expression Set 230	1374451_at	-	-
Rat Expression Set 230	1369817_at	-	-
Rat Expression Set 230	1369817_PM_at	-	-
Rat Expression Set 230	1374451_PM_at	-	-
Affymetrix Rat Gene 1.0 ST Array	10791504	-	-
Rat Genome U34 Set	Y08138_at	-	-

Array Name	Probe IDs	Targets	Target Type
ABI Rat Genome Survey Microarray	21391784	-	-

Array Name	Probe IDs	Targets	Target Type
Illumina ratRef-12 v1.0 expression beadchip	ILMN_1649869	-	-