Rn00578745_g1

• Gene Symbol: Alox15
• Gene Name: arachidonate 15-lipoxygenase
• Gene Aliases: 12-LOX, 15-LOX, Alox12, Alox12l
• Chromosome Location: Chr.10: 56953692 - 56962140 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Alox15
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_031010.2	NP_112272.2	3 - 4	422		82
	XM_006246823.2	XP_006246885.1	5 - 6	703		82
	XM_006246824.2	XP_006246886.1	4 - 5	598		82
GenBank mRNA	L06040.1	-	3 - 4	435		82
	S69383.1	-	3 - 4	422		82

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC1000003125.rn.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Detect Genomic DNA, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Alox15

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

ossification
negative regulation of adaptive immune response
phosphatidylethanolamine biosynthetic process
positive regulation of cell proliferation
positive regulation of cell-substrate adhesion
arachidonic acid metabolic process
lipoxygenase pathway
fatty acid oxidation
bone mineralization
positive regulation of cell growth
positive regulation of actin filament polymerization
positive regulation of heterotypic cell-cell adhesion
response to endoplasmic reticulum stress
regulation of peroxisome proliferator activated receptor signaling pathway
cellular response to interleukin-13
wound healing
regulation of membrane potential
negative regulation of apoptotic process
apoptotic cell clearance
negative regulation of cell volume
icosanoid biosynthetic process
hepoxilin biosynthetic process
oxidation-reduction process
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
regulation of engulfment of apoptotic cell
lipoxin A4 biosynthetic process

Function(s)

arachidonate 12-lipoxygenase activity
iron ion binding
phosphatidylinositol-4,5-bisphosphate binding
potassium channel inhibitor activity
hepoxilin-epoxide hydrolase activity
arachidonate 15-lipoxygenase activity
hepoxilin A3 synthase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR1000028070.rn.1	TC1000003125.rn.1	RTA TC