Rn00678873_g1

• Gene Symbol: Park7
• Gene Name: parkinson protein 7
• Gene Aliases: CAP1, DJ-1, Dj1, SP22
• Chromosome Location: Chr.5: 167982438 - 168004724 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Park7
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001277249.1	NP_001264178.1	2 - 3	209		117
	NM_001277250.1	NP_001264179.1	2 - 3	209		117
	NM_001277251.1	NP_001264180.1	3 - 4	268		117
	NM_001277252.1	NP_001264181.1	2 - 3	149		117
	NM_001277253.1	NP_001264182.1	2 - 3	261		117
	NM_057143.2	NP_476484.1	2 - 3	391		117
GenBank mRNA	AF157511.1	-	2 - 3	391		117
	AF157512.1	-	2 - 3	145		117
	AJ007291.1	-	3 - 4	316		117
	BC091128.1	-	2 - 3	182	7376914	117
	FM055257.1	-	2 - 3	179		117
	FM061417.1	-	2 - 3	130		117
	FM069664.1	-	2 - 3	200		117
	FQ220895.1	-	2 - 3	261		117
	FQ223564.1	-	2 - 3	259		117
	FQ224480.1	-	3 - 4	252		117

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect genomic DNA. Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Detect Genomic DNA, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Park7

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
synaptic transmission, dopaminergic
negative regulation of protein kinase activity
proteolysis
protein deglycosylation
autophagy
inflammatory response
response to oxidative stress
mitochondrion organization
single fertilization
adult locomotory behavior
fertilization
detoxification of copper ion
negative regulation of gene expression
methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
lactate biosynthetic process
negative regulation of protein ubiquitination
negative regulation of protein binding
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of interleukin-8 production
positive regulation of peptidyl-serine phosphorylation
negative regulation of protein sumoylation
cellular response to oxidative stress
cellular response to reactive oxygen species
cellular response to glyoxal
response to drug
response to hydrogen peroxide
hydrogen peroxide metabolic process
negative regulation of apoptotic process
regulation of neuron apoptotic process
negative regulation of neuron apoptotic process
regulation of TRAIL receptor biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
glycolate biosynthetic process
negative regulation of protein export from nucleus
regulation of inflammatory response
detoxification of mercury ion
protein stabilization
positive regulation of sequence-specific DNA binding transcription factor activity
negative regulation of ubiquitin-protein transferase activity
dopamine uptake involved in synaptic transmission
regulation of mitochondrial membrane potential
membrane depolarization
oxidation-reduction process
membrane hyperpolarization
negative regulation of cell death
regulation of androgen receptor signaling pathway
cellular response to hydrogen peroxide
positive regulation of protein homodimerization activity
positive regulation of protein localization to nucleus
negative regulation of neuron death
positive regulation of superoxide dismutase activity
negative regulation of protein acetylation
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of mitochondrial electron transport, NADH to ubiquinone
negative regulation of protein K48-linked deubiquitination
negative regulation of TRAIL-activated apoptotic signaling pathway
positive regulation of pyrroline-5-carboxylate reductase activity
positive regulation of tyrosine 3-monooxygenase activity
positive regulation of dopamine biosynthetic process
glyoxal catabolic process
positive regulation of L-dopa biosynthetic process
positive regulation of L-dopa decarboxylase activity
negative regulation of oxidative stress-induced cell death
negative regulation of hydrogen peroxide-induced cell death
negative regulation of hydrogen peroxide-induced neuron death
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
positive regulation of reactive oxygen species biosynthetic process
negative regulation of ubiquitin-specific protease activity
positive regulation of oxidative phosphorylation uncoupler activity
positive regulation of transcription regulatory region DNA binding
positive regulation of androgen receptor activity
negative regulation of extrinsic apoptotic signaling pathway
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Function(s)

molecular_function
double-stranded DNA binding
single-stranded DNA binding
transcription coactivator activity
mRNA binding
receptor binding
copper ion binding
protein binding
transcription factor binding
peptidase activity
superoxide dismutase copper chaperone activity
oxidoreductase activity, acting on peroxide as acceptor
glyoxalase III activity
enzyme binding
kinase binding
cytokine binding
tyrosine 3-monooxygenase activator activity
L-dopa decarboxylase activator activity
identical protein binding
protein homodimerization activity
small protein activating enzyme binding
ubiquitin-like protein conjugating enzyme binding
mercury ion binding
androgen receptor binding
peroxiredoxin activity
repressing transcription factor binding
scaffold protein binding
cupric ion binding
cuprous ion binding
ubiquitin-specific protease binding
glyoxalase (glycolic acid-forming) activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0500031410.rn.1	TC0500004112.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0500031394.rn.1	TC0500004112.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0500031411.rn.1	TC0500004112.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0500031398.rn.1	TC0500004112.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0500031412.rn.1	TC0500004112.rn.1	RTA TC