Rn00817714_g1

• Gene Symbol: Map2k1
• Gene Name: mitogen activated protein kinase kinase 1
• Gene Aliases: Mek1
• Chromosome Location: Chr.8: 69134218 - 69722252 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Map2k1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_031643.4	NP_113831.1	10 - 11	1113		130
GenBank mRNA	BC089772.1	-	10 - 11	1107	7382030	130
	D13341.1	-	10 - 11	1096		130
	D14591.1	-	10 - 11	1066		130
	X62313.1	-	10 - 11	1103		130
	Z16415.1	-	10 - 11	1096		130

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0800002747.rn.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Protein Kinase, 3' Most, Mammalian Gene Collection, Detect Genomic DNA, Rattus norvegicus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Map2k1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
regulation of vascular smooth muscle contraction
protein phosphorylation
response to oxidative stress
cell cycle arrest
mitotic nuclear division
cell proliferation
negative regulation of cell proliferation
positive regulation of gene expression
peptidyl-tyrosine phosphorylation
neuron differentiation
keratinocyte differentiation
positive regulation of cell migration
melanosome transport
regulation of stress-activated MAPK cascade
positive regulation of transcription elongation from RNA polymerase II promoter
negative regulation of homotypic cell-cell adhesion
peptidyl-tyrosine dephosphorylation
intracellular signal transduction
positive regulation of GTPase activity
positive regulation of cell differentiation
positive regulation of Ras protein signal transduction
vesicle transport along microtubule
Golgi inheritance
response to axon injury
regulation of axon regeneration
neuron projection morphogenesis
cell motility
positive regulation of axonogenesis
protein heterooligomerization
response to glucocorticoid
lung morphogenesis
trachea formation
epithelial cell proliferation involved in lung morphogenesis
placenta blood vessel development
labyrinthine layer development
ERK1 and ERK2 cascade
positive regulation of protein serine/threonine kinase activity
regulation of Golgi inheritance
cellular senescence
regulation of early endosome to late endosome transport

Function(s)

protein serine/threonine kinase activity
MAP kinase kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
receptor signaling protein tyrosine phosphatase activity
protein binding
ATP binding
Ras GTPase binding
protein kinase binding
mitogen-activated protein kinase kinase kinase binding
protein serine/threonine kinase activator activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Agilent Whole Rat Genome Microarray 4x44K v2	A_44_P531063	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	115691	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	513930	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	492889	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	809513	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	680103	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	533685	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	622682	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	801478	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	66576	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	912219	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	296355	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	971340	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	809583	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	531801	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	952116	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	135950	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	546867	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	424327	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	409550	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	77910	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	776837	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	740144	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	582816	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	765235	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	618637	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	246935	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	620654	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	653717	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	721146	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	912406	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	353723	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	906806	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	660508	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	703628	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	905540	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	536955	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	378410	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	224489	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	193955	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	818529	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	730220	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	822025	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	530748	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	775226	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	351274	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	340359	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	764912	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	808562	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	65126	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	579139	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	107355	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	17217	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	55394	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	136833	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	105261	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	156187	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	146999	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	113135	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_44_P531063	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_44_P531063	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_44_P531063	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_44_P531063	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	48070	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	18162	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	5814	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	54976	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	103201	-	-

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Gene 1.0 ST Array	10918220	-	-
Affymetrix Rat Gene 1.0 ST Array	10918213	-	-
Affymetrix Rat Gene 1.0 ST Array	10918215	-	-
Affymetrix Rat Gene 1.0 ST Array	10918219	-	-
Affymetrix Rat Gene 1.0 ST Array	10918212	-	-
Affymetrix Rat Gene 1.0 ST Array	10918210	-	-
Affymetrix Rat Gene 1.0 ST Array	10918211	-	-
Affymetrix Rat Gene 1.0 ST Array	10918221	-	-
Affymetrix Rat Gene 1.0 ST Array	10918216	-	-
Affymetrix Rat Gene 1.0 ST Array	10918214	-	-
Affymetrix Rat Gene 1.0 ST Array	10918217	-	-
Affymetrix Rat Gene 1.0 ST Array	10918218	-	-
Affymetrix Rat Gene 1.1 ST Array	10918209	-	-
Rat Genome 230 2.0 Array	1367760_PM_at	-	-
Rat Genome 230 2.0 Array	1367760_at	-	-
Affymetrix HT Rat Focus Array	1367760_PM_at	-	-
Affymetrix HT Rat Focus Array	1367760_at	-	-
Affymetrix Rat Clariom S Assay	PSR0800022333.rn.1	TC0800002747.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0800022332.rn.1	TC0800002747.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0800022334.rn.1	TC0800002747.rn.1	RTA TC
Rat Expression Set 230	1367760_PM_at	-	-
Rat Expression Set 230	1367760_at	-	-
Affymetrix Rat Gene 1.0 ST Array	10918209	-	-
Rat Genome U34 Set	D14591_s_at	-	-
Rat Genome U34 Set	L04485mRNA_s_at	-	-
Rat Genome U34 Set	rc_AI178835_at	-	-
Rat Genome U34 Set	D14591_s_at	-	-
Rat Genome U34 Set	L04485mRNA_s_at	-	-
Rat Genome U34 Set	rc_AI178835_at	-	-
Rat Genome U34 Set	rc_AI178835_at	-	-
Rat Genome U34 Set	D14591_s_at	-	-
Rat Genome U34 Set	L04485mRNA_s_at	-	-

Array Name	Probe IDs	Targets	Target Type
ABI Rat Genome Survey Microarray	21080101	-	-

Array Name	Probe IDs	Targets	Target Type
Illumina ratRef-12 v1.0 expression beadchip	ILMN_1361975	-	-
RatRef-12 Expression BeadChip	ILMN_59171	-	-