Rn00821185_g1

• Gene Symbol: Apex1
• Gene Name: APEX nuclease (multifunctional DNA repair enzyme) 1
• Gene Aliases: APE, Apex, REF-1
• Chromosome Location: Chr.15: 27849943 - 27852083 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Apex1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_024148.1	NP_077062.1	2 - 3	160		86
	XM_006251913.1	XP_006251975.1	2 - 3	201		86
GenBank mRNA	AF309114.1	-	1 - 2	76		86
	AF311054.1	-	1 - 2	38		86
	BC078816.1	-	2 - 3	168	7127205	86
	D44495.1	-	2 - 3	160		86
	FQ220521.1	-	2 - 3	162		86

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect genomic DNA. Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Detect Genomic DNA, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Apex1

Gene Ontology Categories:

Process(es)

DNA catabolic process, endonucleolytic
DNA catabolic process, exonucleolytic
DNA repair
base-excision repair
DNA recombination
transcription, DNA-templated
regulation of transcription, DNA-templated
aging
response to organonitrogen compound
negative regulation of smooth muscle cell migration
response to drug
regulation of mRNA stability
cell redox homeostasis
positive regulation of DNA repair
oxidation-reduction process
cellular response to hydrogen peroxide
cellular response to cAMP
cellular response to peptide hormone stimulus
cellular response to organonitrogen compound
DNA demethylation
nucleic acid phosphodiester bond hydrolysis
RNA phosphodiester bond hydrolysis, endonucleolytic
positive regulation of G1/S transition of mitotic cell cycle

Function(s)

DNA binding
damaged DNA binding
transcription coactivator activity
DNA-(apurinic or apyrimidinic site) lyase activity
endonuclease activity
endoribonuclease activity
protein binding
phosphoric diester hydrolase activity
double-stranded DNA 3'-5' exodeoxyribonuclease activity
3'-5' exonuclease activity
oxidoreductase activity
site-specific endodeoxyribonuclease activity, specific for altered base
chromatin DNA binding
protein complex binding
poly(A) RNA binding
metal ion binding
NF-kappaB binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR1500002034.rn.1	TC1500000297.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR1500002032.rn.1	TC1500000297.rn.1	RTA TC