Rn01416753_m1 Best Coverage

• Gene Symbol: Pcsk9
• Gene Name: proprotein convertase subtilisin/kexin type 9
• Gene Aliases: NARC-1, Narc1, PC9
• Chromosome Location: Chr.5: 126031368 - 126053726 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Pcsk9
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_199253.2	NP_954862.2	11 - 12	2054		82
GenBank mRNA	AY847775.1	-	11 - 12	2054		82
	BC133063.1	-	11 - 12	1985	8371686	82
	FQ219599.1	-	2 - 3	282		82

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0500003281.rn.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Protease, 3' Most, Mammalian Gene Collection, Recommended Assay, Rattus norvegicus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Pcsk9

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

kidney development
liver development
negative regulation of receptor recycling
positive regulation of receptor internalization
proteolysis
triglyceride metabolic process
phospholipid metabolic process
apoptotic process
lysosomal transport
cholesterol metabolic process
cellular response to starvation
regulation of receptor activity
negative regulation of low-density lipoprotein particle clearance
protein processing
protein autoprocessing
neurogenesis
neuron differentiation
low-density lipoprotein receptor particle metabolic process
low-density lipoprotein particle receptor catabolic process
regulation of low-density lipoprotein particle receptor catabolic process
cellular response to insulin stimulus
lipoprotein metabolic process
cholesterol homeostasis
regulation of neuron apoptotic process
positive regulation of neuron apoptotic process

Function(s)

serine-type endopeptidase activity
sodium channel inhibitor activity
low-density lipoprotein particle binding
apolipoprotein binding
very-low-density lipoprotein particle binding
apolipoprotein receptor binding
protein self-association
poly(A) RNA binding
low-density lipoprotein particle receptor binding
very-low-density lipoprotein particle receptor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Agilent Whole Rat Genome Microarray 4x44K v2	A_64_P021043	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	323156	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	365366	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	139631	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	715495	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	617777	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	385193	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	32646	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	633223	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	313293	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	597200	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	456726	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	784855	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	511117	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	876022	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	142682	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	164027	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	792429	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	307334	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	27993	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	155801	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	3785	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P021043	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P021043	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_64_P021043	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_43_P20129	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	23969	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	47661	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	32488	-	-

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Gene 1.0 ST Array	10878444	-	-
Affymetrix Rat Gene 1.0 ST Array	10878445	-	-
Affymetrix Rat Gene 1.0 ST Array	10878437	-	-
Affymetrix Rat Gene 1.0 ST Array	10878447	-	-
Affymetrix Rat Gene 1.0 ST Array	10878441	-	-
Affymetrix Rat Gene 1.0 ST Array	10878440	-	-
Affymetrix Rat Gene 1.0 ST Array	10878436	-	-
Affymetrix Rat Gene 1.0 ST Array	10878446	-	-
Affymetrix Rat Gene 1.0 ST Array	10878443	-	-
Affymetrix Rat Gene 1.0 ST Array	10878438	-	-
Affymetrix Rat Gene 1.0 ST Array	10878442	-	-
Affymetrix Rat Gene 1.0 ST Array	10878439	-	-
Affymetrix Rat Gene 1.1 ST Array	10878435	-	-
Rat Genome 230 2.0 Array	1385640_PM_at	-	-
Rat Genome 230 2.0 Array	1385640_at	-	-
Affymetrix HT Rat Focus Array	1385640_PM_at	-	-
Affymetrix HT Rat Focus Array	1385640_at	-	-
Affymetrix Rat Clariom S Assay	PSR0500023772.rn.1	TC0500003281.rn.1	RTA TC
Rat Expression Set 230	1385640_at	-	-
Rat Expression Set 230	1385640_PM_at	-	-
Affymetrix Rat Gene 1.0 ST Array	10878435	-	-
Rat Genome U34 Set	rc_AI059511_at	-	-

Array Name	Probe IDs	Targets	Target Type
ABI Rat Genome Survey Microarray	22168935	-	-

Array Name	Probe IDs	Targets	Target Type
Illumina ratRef-12 v1.0 expression beadchip	ILMN_1370891	-	-
RatRef-12 Expression BeadChip	ILMN_47967	-	-