Rn01433339_m1

• Gene Symbol: Tek
• Gene Name: TEK tyrosine kinase, endothelial
• Gene Aliases: Tie-2, Tie2
• Chromosome Location: Chr.5: 113725717 - 113852799 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Tek
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001105737.1	NP_001099207.1	15 - 16	2897		73
	XM_008763910.1	XP_008762132.1	15 - 16	2717		73

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0500000993.rn.1

• Set Membership: Amplicon length between 71 and 85, Protein Kinase, Rattus norvegicus, Probe spans exons

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

angiogenesis
vasculogenesis
response to hypoxia
positive regulation of protein phosphorylation
endothelial cell proliferation
endochondral ossification
sprouting angiogenesis
positive regulation of cytokine secretion involved in immune response
cell-matrix adhesion
transmembrane receptor protein tyrosine kinase signaling pathway
heart development
response to organic substance
positive regulation of endothelial cell migration
positive regulation of phosphatidylinositol 3-kinase signaling
single organismal cell-cell adhesion
negative regulation of angiogenesis
peptidyl-tyrosine phosphorylation
signal transduction by protein phosphorylation
hemopoiesis
regulation of cell migration
organ regeneration
response to retinoic acid
regulation of establishment or maintenance of cell polarity
positive regulation of peptidyl-serine phosphorylation
substrate adhesion-dependent cell spreading
intracellular signal transduction
positive regulation of protein import into nucleus
negative regulation of apoptotic process
response to peptide hormone
positive regulation of phosphatidylinositol 3-kinase activity
response to estrogen
regulation of angiogenesis
positive regulation of angiogenesis
positive regulation of cell adhesion
protein autophosphorylation
Tie signaling pathway
protein oligomerization
response to cAMP
positive regulation of focal adhesion assembly
positive regulation of protein kinase B signaling
heart trabecula formation
positive regulation of ERK1 and ERK2 cascade
regulation of NIK/NF-kappaB signaling
positive regulation of intracellular signal transduction
positive regulation of actin cytoskeleton reorganization
negative regulation of endothelial cell apoptotic process

Function(s)

protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
receptor signaling protein tyrosine kinase activity
receptor activity
ATP binding
growth factor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0500006259.rn.1	TC0500000993.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0500006260.rn.1	TC0500000993.rn.1	RTA TC